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| Product Name: | ZL0420 | | Synonyms: | ZL0420;CS-2832;ZL 0420 ;ZL0420 ;ZL-0420;ZL 0420;ZL-0420;2(1H)-Quinolinone, 6-[2-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-3,4-dihydro-;inhibit,Epigenetic Reader Domain,(E/Z)-ZL0420,BRD4,airway inflammation,immune response genes,ZL0420,BET,ZL-0420,bromodomains,Inhibitor;6-((2-Amino-4-hydroxy-5-methylphenyl)diazenyl)-3,4-dihydroquinolin-2(1H)-one;(E/Z)-ZL0420 | | CAS: | 2229039-45-4 | | MF: | C16H16N4O2 | | MW: | 296.32 | | EINECS: | | | Product Categories: | | | Mol File: | 2229039-45-4.mol |  |
| | ZL0420 Chemical Properties |
| Boiling point | 645.9±55.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml | | form | A crystalline solid | | pka | 9.20±0.40(Predicted) |
| | ZL0420 Usage And Synthesis |
| Description | ZL0420 is a potent and selective BRD4 inhibitor. ZL0420 reduces airway inflammation and inhibits the TLR3-dependent innate immune gene program, including ISG54, ISG56, IL-8, and Groβ genes in cultured human small airway epithelial cells (hSAECs). |
| | ZL0420 Preparation Products And Raw materials |
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