| Company Name: |
Beijing HwrkChemical Technology Co., Ltd
|
| Tel: |
18515581800 18501085097 |
| Email: |
sales.bj@hwrkchemical.com |
| Products Intro: |
Product Name:6-acetyl-8-cyclopentyl-5-methyl-1H-pyrido[2,3-d]pyrimidine-2,7-dione
CAS:2172256-78-7
Purity:97% Package:1g/5g/100g Remarks:HWRK087898
|
| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
|
| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:6-acetyl-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
CAS:2172256-78-7
Purity:95%HPLC Package:10MG;25MG;50MG;100MG Remarks:DCTI-C-2117
|
|
| | Palbociclib Impurity I Basic information |
| Product Name: | Palbociclib Impurity I | | Synonyms: | 6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione;Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione, 6-acetyl-8-cyclopentyl-5-methyl-;6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione;6-Acetyl-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity);6-acetyl-8-cyclopentyl-5-methyl-1H-pyrido[2,3-d]pyrimidine-2,7-dione | | CAS: | 2172256-78-7 | | MF: | C15H17N3O3 | | MW: | 287.31 | | EINECS: | | | Product Categories: | | | Mol File: | 2172256-78-7.mol |  |
| | Palbociclib Impurity I Chemical Properties |
| Melting point | >201°C (dec.) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 10.09±0.60(Predicted) | | form | Solid | | color | Light Beige to Brown |
| | Palbociclib Impurity I Usage And Synthesis |
| Uses | 6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer. |
| | Palbociclib Impurity I Preparation Products And Raw materials |
|