| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:Tyrphostin AG1433
CAS:168835-90-3
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
ShangHai Biochempartner Co.,Ltd
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| Tel: |
17754423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:Tyrphostin AG1433
CAS:168835-90-3
Purity:98% HPLC LCMS Package:100mg;500mg;1g
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| Company Name: |
Zhengzhou Huiju Chemical Co., Ltd.
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| Tel: |
0371-55900031 18137872243 |
| Email: |
2853979815@qq.com |
| Products Intro: |
Product Name:4-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol
CAS:168835-90-3
Purity:98% Package:1g ；5g ；10g ；25g ；100g ；500g ；1kg ；5kg ；10kg ；25kg ；100kg
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| | Tyrphostin AG1433 Basic information |
| Product Name: | Tyrphostin AG1433 | | Synonyms: | 1,2-Benzenediol, 4-(6,7-dimethyl-2-quinoxalinyl)-;cytotoxicity,PDGFRβ,Tyrphostin AG 1433,AG-1433,Tyrphostin AG1433,VEGFR,AG 1433,kinases,Vascular endothelial growth factor receptor,SU 1433,Tyrphostin AG-1433,Platelet-derived growth factor receptor,angiogenesis,tyrosine,inhibit,VEGFR-2,Inhibitor,ATM,PDGFR,SU-1433 | | CAS: | 168835-90-3 | | MF: | C16H14N2O2 | | MW: | 266.29 | | EINECS: | | | Product Categories: | | | Mol File: | 168835-90-3.mol |  |
| | Tyrphostin AG1433 Chemical Properties |
| Melting point | 280-282 °C | | Boiling point | 490.9±45.0 °C(Predicted) | | density | 1.300±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 62.5 mg/mL (234.71 mM) | | pka | 8.32±0.20(Predicted) |
| | Tyrphostin AG1433 Usage And Synthesis |
| Biological Activity | Tyrphostin AG1433 (SU1433) is a tyrosine kinase inhibitor. It is also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with IC50 of 5.0 μM and 9.3 μM, respectively. It prevents blood vessel formation. | | in vivo | Chorion allantoic membrane (CAM) assays are used to determine the effects of the Flk-i inhibitors on angiogenesis. Tyrphostin AG1433 (SU1433) is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day- old chicken embryos. Tyrphostin AG1433 prevents the formation of new yessels under the pellets. | | target | | Flk-1 < span> 9.3 μM (IC 50 ) | PDGFRβ 5 μM (IC 50 ) | |
| | Tyrphostin AG1433 Preparation Products And Raw materials |
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