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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
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Product Name:Bis-(3,4,5-triMethoxyphenyl)-1,3-dioxolane
CAS:116673-45-1
Package:50Mg,5Mg
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037 |
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Product Name:BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE
CAS:116673-45-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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021-50135380 |
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shchemsky@sina.com |
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Product Name:Bis-(3,4,5-triMethoxyphenyl)-1,3-dioxolane;(2R,4R)-rel-2,4-Bis(3,4,5-triMethoxyphenyl)-1,3-dioxolane; trans-2,4-Bis(3,4,5-triMethoxyphenyl)-1,3-dioxolane;
CAS:116673-45-1
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627 |
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info@efebio.com |
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Product Name:(±)-trans-2，5-Bis-(3，4，5-trimethoxyphenyl)-1，3-dioxolane
CAS:116673-45-1
Purity:98% (TLC) Package:1mg;5mg;10mg
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| | BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Basic information |
| Product Name: | BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE | | Synonyms: | BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;TRANS-BTP DIOXOLANE;(+/-) TRANS-2,5-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;TRANS-(+/-)-2,4-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;(2R,4R)-rel-2,4-Bis(3,4,5-triMethoxyphenyl)-1,3-dioxolane;1,3-Dioxolane, 2,4-bis(3,4,5-trimethoxyphenyl)-, (2R,4R)-rel- | | CAS: | 116673-45-1 | | MF: | C21H26O8 | | MW: | 406.43 | | EINECS: | | | Product Categories: | Aromatics Compounds;Aromatics;Heterocycles | | Mol File: | 116673-45-1.mol |  |
| | BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Chemical Properties |
| Boiling point | 508.3±50.0 °C(Predicted) | | density | 1.184±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | ≤35mg/ml in ethanol;50mg/ml in DMSO;50mg/ml in dimethyl formamide | | form | White to off-white solid. |
| | BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Usage And Synthesis |
| Uses | A potent and selective platlet activating factor | | Biological Activity | (±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane, also known as trans-btp dioxolane, is a paf receptor antagonist [1].platelet activating factor (paf), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. paf also stimulates the production of active oxygen species by human monocyte - derived macrophages. paf play important roles in a variety of pathophysiological states including acute allergy, inflammation, asthma, gastrointestinal ulceration, and toxic shock [1].(±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane is a paf receptor antagonist. in the rabbit washed platelet assay, (±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane showed good competitive paf antagonism with ki value of 0.3 μm, whereas the cis-isomer was much less active. | | references | [1]. corey, e.j.,chen, c.p., and parry, m.j. dual binding modes to the receptor for platelet activating factor (paf) of anti-paf trans-2,5-diarylfurans. tetrahedron letters 29, 2899-2902 (1988). |
| | BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Preparation Products And Raw materials |
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