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ChemicalBook Optimization Suppliers |
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| 化学名: | (R)-ズロキセチン | | 英語化学名: | (R)-Duloxetine | | 别名: | (r)-duloxetine;(r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine;R-DULOXETINE HCL;(R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride;N-methyl-3-(1-naphthalenyloxy)-3-thiophen-2-yl-1-propanamine;Ariclaim;CYMBALTA; ARICLAIM;2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR) | | CAS番号: | 116539-60-7 | | 分子式: | C18H19NOS | | 分子量: | 297.41 | | EINECS: | 1312995-182-4 | | カテゴリ情報: | Pharmaceutical intermediate | | Mol File: | 116539-60-7.mol |  |
| 沸点 | 466.2±40.0 °C(Predicted) | | 比重(密度) | 1.158 | | 酸解離定数(Pka) | 10.02±0.10(Predicted) |
| | (R)-ズロキセチン Usage And Synthesis |
| 使用 | (R)-Duloxetine is a dual inhibitor of serotonin and norepinephrine reuptake, effective in the treatment of emotional and physical symptoms of depression | | 定義 | ChEBI: (R)-duloxetine is a duloxetine. It is an enantiomer of a (S)-duloxetine. | | 主な応用 | Duloxetine (duloxetine) is a third-generation antidepressant launched in 2002, and its hydrochloride is clinically used under the trade name Cymbalta (Cymbalta). | | 合成 | (R)-Duloxetine was prepared from (S)-3-N,N-dimethylamino-1-(2-thienyl)-1-propanol 67. |
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