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CLEARSYNTH LABS LTD.
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+91-22-45045900 |
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Products Intro: |
Product Name:Hexylcaine CAS:532-77-4
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| Hexylcainc Basic information |
Product Name: | Hexylcainc | Synonyms: | Hexylcainc;1-(Cyclohexylamino)-2-propanol benzoate;Benzoic acid 1-(cyclohexylamino)-2-methylethyl ester;Benzoic acid 2-cyclohexylamino-1-methylethyl ester;2-Propanol, 1-(cyclohexylamino)-, 2-benzoate;1-(cyclohexylamino)propan-2-yl benzoate | CAS: | 532-77-4 | MF: | C16H23NO2 | MW: | 261.36 | EINECS: | | Product Categories: | | Mol File: | 532-77-4.mol | |
| Hexylcainc Chemical Properties |
Boiling point | 385.3±25.0 °C(Predicted) | density | 1.05±0.1 g/cm3(Predicted) | solubility | soluble in Dichloromethane | form | Solid | pka | 9.02±0.20(Predicted) | color | White |
Toxicity | LDLo par-man: 11 mL/kg:BAH,PUL JFSCAS5,501,1960 |
| Hexylcainc Usage And Synthesis |
Originator | Cyclaine,MSD,US,1952 | Uses | Hexylcaine is an intermediate in the synthesis of Hexylcaine Hydrochloride which is used in pain management in as an antifungal agent. Anaesthetic. | Definition | ChEBI: Hexylcaine is a benzoate ester. | Manufacturing Process | A solution of 0.1 mol of 1-cyclohexylamino-2-propanol in 30 grams of
chloroform was saturated with dry hydrogen chloride gas, with cooling. A
solution of 0.1 mol of benzoyl chloride in 30 grams of chloroform was added
and the solution was heated in a bath at 50° to 55°C for four days under a
reflux condenser protected from atmospheric moisture. Then the solvent was
removed by vacuum distillation while the mixture was warmed on a water
bath. Benzene was then added to the syrupy residue and the reaction product
crystallized out after the benzene was removed by vacuum distillation.
The crystallized solid residue was washed with anhydrous ether to remove any
unreacted benzoyl chloride. The 1-cyclohexylamino-2-propyl benzoate
hydrochloride obtained was purified by two recrystallizations from absolute
alcohol. It melted at 177° to 178.5°C. | Therapeutic Function | Local anesthetic | Safety Profile | Human systemic effects. When heated to decomposition it emits toxic vapors of NOx. |
| Hexylcainc Preparation Products And Raw materials |
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