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| 化学名: | シロマジン | | 英語化学名: | Cyromazine | | 别名: | Vetrazin【pesticide】;Cyromazine, 2-Cyclopropylamino-4,6-diamino-s-triazine;N-Cyclopropyl;5-triazine-2,4,6-triamine,n-cyclopropyl-3;ai3-52713;cga72662;neoprex;Cyromazine (200 mg) | | CAS番号: | 66215-27-8 | | 分子式: | C6H10N6 | | 分子量: | 166.18 | | EINECS: | 266-257-8 | | カテゴリ情報: | Pharmaceutical intermediate;Pesticide;Acaricides;Analytical Standards;Analytical/Chromatography;Building Blocks;Chemical Synthesis;Chromatography;Environmental Standards;Heterocyclic Building Blocks;Metabolites;Pesticides;Pesticides &;Triazines;Pesticide intermediates;fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis, insecticide;Bases & Related Reagents;Heterocycles;Nucleotides;INSECTICIDE;FINE Chemical & INTERMEDIATES;Active Pharmaceutical Ingredients;66215-27-8 | | Mol File: | 66215-27-8.mol |  |
| 融点 | 223-227 °C (lit.) | | 沸点 | 284.39°C (rough estimate) | | 比重(密度) | 1.3196 (rough estimate) | | 蒸気圧 | 4.5 x l0-7 Pa (25 °C) | | 屈折率 | 1.8300 (estimate) | | 闪点 | 100 °C | | 貯蔵温度 | 2-8°C | | 溶解性 | DMSO (Slightly), Methanol (Slightly) | | 酸解離定数(Pka) | 5.2 (base) | | 水溶解度 | 13 g l-1 (pH 7.1,25 °C) | | 色 | White to Off-White | | Merck | 14,2775 | | BRN | 882879 | | 安定性： | Hygroscopic | | InChIKey | LVQDKIWDGQRHTE-UHFFFAOYSA-N | | LogP | -0.061 at 25℃ | | CAS データベース | 66215-27-8(CAS DataBase Reference) | | NISTの化学物質情報 | Cyromazine(66215-27-8) | | EPAの化学物質情報 | Cyromazine (66215-27-8) |
| 主な危険性 | Xi | | Rフレーズ | 36/37/38 | | Sフレーズ | 26-36 | | RIDADR | UN3077 (solid) | | WGK Germany | 2 | | RTECS 番号 | XZ1056500 | | HSコード | 29336990 | | 有毒物質データの | 66215-27-8(Hazardous Substances Data) | | 毒性 | LC50 (96-hour) for rainbow trout and carp >100 mg/L and bluegill sunfish >90
mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats 3,387 mg/kg (Hartley and Kidd,
1987) |
| | シロマジン Usage And Synthesis |
| 外観 | 白色, 結晶～粉末 | | 溶解性 | 水 (13g/l)。水に溶ける。 | | 効能 | 抗寄生虫薬, 殺虫薬 (獣医薬) | | 農薬用途 | 動物薬、殺虫剤 | | 化学的特性 | White crystalline powder. The solubility in water is 11,000 mg/L at 20°C and pH 7.5, and the hydrolysis is not obvious at pH 5-9. | | 使用 | Cypromazine is a high-efficiency and low-toxicity insecticide. It is mainly used to control leafminer pests, has a good control effect on Liriomyza, and can also be used to control flies. | | 主な応用 | Cyromazine is an insect growth regulator, used to control fly larvae in livestock and poultry manure. It can be fed directly to livestock or applied directly to fly breeding sites. Cyromazine also exhibits systemic activity and is used as a foliar spray to control leaf miners in vegetables, potatoes, etc., and on mushrooms. | | 製造方法 | Cyromazine is prepared by the reaction of cyanuric chloride and cyclopropylamine to obtain 2-Cyclopropylamino-4,6-dichloro-triazepine, and then reacts with ammonia to obtain 2-Cyclopropylamino-4-chloro-6-aminostriazepine, and then reacting with ammonia to produce. | | 定義 | ChEBI: Cyromazine is a triamino-1,3,5-triazine. It has a role as a triazine insecticide and a mouse metabolite. | | 一般的な説明 | N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine, also known as cyromazine, is an insect growth regulator(IGR) that is commonly used as an insecticide. It undergoes metabolism in plants and animals to form melamine. Surface-enhanced Raman scattering (SERS) spectroscopic study indicates that it interacts with the surface of silver colloid through the lone pair on nitrogen. | | 燃焼性と爆発性 | Not classified | | 农业用途 | Insecticide (insect growth regulator): As an insect growth regulator, cyromazine is fed to caged poultry and is passed through the chicken, leaving a residue in the manure. The chemical controls the growth of the fly larvae developing in the manure. Used as a foliar spray to control leaf miners in vegetables, mushrooms, potatoes and ornamentals and to control flies on animals. | | 製品名 | ARMOR®; CITATION; CGA-72662®; LARVADEX®; PATRON®; TRIGARD®; VETRAZIN® | | 環境運命予測 | Chemical/Physical. Cyromazine will react with mineral acids (e.g., hydrochloric acid,
sulfuric acid) forming water-soluble salts | | 代謝経路 | Information presented in this summary is abstracted from the data evaluation
published by the Pesticide Safety Directorate (PSD, 1993). The major
degradation pathway of cyromazine involves the N-dealkylation of the
cyclopropyl moiety to yield melamine. Both cyromazine and melamine are
quite stable to biotransformation. Deamination and the formation of
N-methylcyromazine were observed as minor pathways. | | Degradation | Cyromazine (1) is stable to hydrolysis at pH 5, 7 and 9 and 70 °C
for up to 28 days. No degradation of cyromazine was observed when
irradiated under mercury vapour lamp (>290 nm) at 25 °C for up to 168 hours. |
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