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| 化学名: | ヒドロキシアパタイト | | 英語化学名: | Hydroxyapatite | | 别名: | CALCIUM PHOSPHATE, HYDROXIDE PURIFIED;Hydroxyapatite: (Calcium hydroxyapatite);Calcium phosphate hydroxide, Durapatite, Hydroxylapatite;CALCIUM PHOSPHATE, HYDROXIDE REAGENT;Hydroxyapatite,Calcium hydroxyphosphate, Calcium phosphate tribasic, HAp, Hydroxylapatite;Hydroxylapatite, for analysis 25GR;apatite,hydroxy;Bonedust | | CAS番号: | 1306-06-5 | | 分子式: | Ca5HO13P3 | | 分子量: | 502.31 | | EINECS: | 215-145-7 | | カテゴリ情報: | raw materials;Inorganics | | Mol File: | 1306-06-5.mol |  |
| | ヒドロキシアパタイト Usage And Synthesis |
| 外観 | 白色の粉末 | | 定義 | 本品は、リン酸塩鉱石から得られる無機物であり、次の化学式で表される。 | | 溶解性 | 水に難溶。希塩酸に可溶, エタノールに不溶。塩酸に溶ける。 | | 解説 | Ca5(OH)(PO4)3(502.32)．骨や歯の構成成分．水に不溶の結晶．タンパク質などをよく吸着するので，クロマトグラフィー用の担体としても使われる．[CAS 1306-06-5]
森北出版「化学辞典（第2版） | | 用途 | 人工骨など生体材料の研究。 | | 用途 | HPLC用カラム充填剤。 | | 用途 | 分取クロマトグラフ充填剤。 | | 用途 | セラミック、歯磨用 | | 化粧品の成分用途 | 口腔ケア剤、研磨.スクラブ剤、増量剤 | | 効能 | 補綴補助 | | 特長 | 1. 粒子を5μmのブロック状に粒子化したアパタイトです。2. HPLCに匹敵する分離能です。3. 高流速が得られます。 | | 特長 | 1. 平均粒子径を40μmにそろえた球状アパタイトです。2.球 状なので取扱いが簡単です。3. 高流速が得られます。4. 耐久性に優れた大型カラムができます。 | | 説明 | Calcium hydroxyapatite has a unique structure in
that it is conductive along the hydroxide channels.
OH- ions lie at (1/4/,1/4,1/4) and (3/4/,3/4,3/4) on
the c-axis and charge-carrying protons are responsible
for the observed conductivities in M10(PO4)6(OH)2. The
H+ migration between the electroattractive ion (O2)
to give molecular H2O in matrix channels carries charge
and the resulting conductivity.
The unit cell consists of two triangular prismatic subcells
forming a rhombic prism with vertical sides. There
are two horizontal mirror planes at the OH levels of 1/4
and 3/4 of the c-axis. In addition, there is a center of
inversion exactly in the center of each vertical face of
each subcell. | | 化学的特性 | Tricalcium phosphate is an odorless and tasteless powder that is stable in air. Tribasic calcium phosphate consists of a
variable mixture of calcium phosphates having the approximate composition of 10CaO·3P2O5·H2O. | | 化学的特性 | white powder | | 天然物の起源 | Occurs in nature as the minerals: oxydapatit, voelicherite, whitlockite. | | 使用 | In the 1970s, it was found that sintered calcium
hydroxyapatite, (Ca10(PO4)6(OH)2 (abbreviated as
CaHap), possessed excellent biocompatibility and nontoxicity
with femur and mandible bones. Since then,
CaHap has been used as a biomaterial for artificial teeth
and bones and as a filler for cements and polymers.
Today, bone fillers made of CaHap are widely used in
the medical and dental fields. In the 1980s, it was found
that sintered CaHap has a good compatibility with skin
tissues. Hence, percutaneous devices based on CaHap
have been developed and applications have included
continuous ambulatory peritoneal dialysis and intravenous
hyperalimentation systems, blood pressure
measurement and blood access for nutrition. Recently,
many researchers have studied the chemistry of apatites,
particularly CaHap, and have found various applications,
such as artificial teeth and bones, ion exchangers,
adsorbents for chromatography to separate proteins and
enzymes, catalysts, ionic conductors, temperature and
gas sensors, etc. | | 使用 | Hydroxyapatite and tricalcium phosphate are bioactive ceramic materials and they find applications as bone grafts, fillers and coating material for metal implants. | | 使用 | Prosthetic aid (artificial bone and teeth). | | 製造方法 | The technical product is also known as “bone ash.” Commercial preparation from phosphate rock. | | 定義 | The major constituent of bone and tooth mineral. It is finely divided, crystalline, nonstoichiometric material rich in surface ions (carbonate, magnesium, citrate), which are readily replaced by fluoride ion, thus affording protection to the teeth. | | brand name | Alveograf (Sterling Winthrop); Periograf (Sterling Winthrop). | | 一般的な説明 | Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied. | | 燃焼性と爆発性 | Not classified | | 応用例（製薬） | Modified hydroxylapatite, also frequently called hydroxyapatite and better known as bone mineral, makes
up ～50% of our bones. Hydroxylapatite is a natural form of the mineral calcium apatite, whose formula is usually denoted as Ca10(PO4)6(OH)2. Modifications of hydroxylapatite can also be found in the teeth, and a
chemically identical substance is often used as filler for replacement of bones, and so on. Nevertheless, despite
similar or identical chemical compositions, the response of the body to these compounds can be quite different. |
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