| Company Name: |
Chengdu Biopurify Phytochemicals Ltd.
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| Tel: |
+86-028-82633397 18982077548 |
| Email: |
cwb1@biopurify.cn |
| Products Intro: |
Product Name:Hamaudol
CAS:735-46-6
Purity:>95%,98%,99% Package:From mgs to grams,up to Kgs.Inquire for Bulk scale.
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| | hamaudol Basic information |
| Product Name: | hamaudol | | Synonyms: | hamaudol;(S)-3,4-Dihydro-3β,5-dihydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one;2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-3,5-dihydroxy-2,2,8-trimethyl-, (3S)-;Inhibitor,COX,Hamaudol,Cyclooxygenase,inhibit | | CAS: | 735-46-6 | | MF: | C15H16O5 | | MW: | 276.28 | | EINECS: | | | Product Categories: | | | Mol File: | 735-46-6.mol |  |
| | hamaudol Chemical Properties |
| Melting point | 197.0-197.5 °C | | Boiling point | 464.7±45.0 °C(Predicted) | | density | 1.336±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 6.77±0.70(Predicted) |
| | hamaudol Usage And Synthesis |
| Definition | ChEBI: Hamaudol is a member of chromenes. | | Biological Activity | Hamaudol is a chromone isolated from Saposhnikovia divaricata. It has obvious inhibitory ability on the activities of cyclooxygenase (COX)-1 and COX-2 with IC50 values of 0.30 and 0.57 mM, respectively, and has potent analgesic and anti-inflammatory effects. | | in vivo | Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency. < b> | | target | | COX-1 < span> 0.3 mM (IC 50 ) | COX-2 0.57 mM (IC 50 ) | |
| | hamaudol Preparation Products And Raw materials |
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