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Naringenin

Naringenin Suppliers list
Company Name: NanJing Spring & Autumn Biological Engineering CO., LTD.
Tel: +8613815430202
Email: sale02@cqherb.com
Products Intro: Product Name:(s)-Naringenin 480-41-1
CAS:480-41-1
Purity:>=98% Package:1g;20.00USD
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:(s)-Naringenin 480-41-1
CAS:480-41-1
Purity:99% Package:25KG;5KG;1KG
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: +8615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:Naringenin fandachem
CAS:480-41-1
Purity:As coa Package:As request Remarks:480-41-1
Company Name: Nanjing Finetech Chemical Co., Ltd.
Tel: 025-85710122 17714198479
Email: sales@fine-chemtech.com
Products Intro: CAS:480-41-1
Purity:99%min Package:1KG;10KG;100KG;500KG;100g Remarks:ISO certified
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:(S)-Naringenin
CAS:480-41-1
Purity:HPLC>=98% Package:20mg

Naringenin manufacturers

  • Naringenin
  • $0.00 / 1kg
  • 2022-05-24
  • CAS:480-41-1
  • Min. Order: 1kg
  • Purity: 95%,98%
  • Supply Ability: 100kg
  • Naringenin
  • $80.00 / 1kg
  • 2022-05-11
  • CAS:480-41-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 80MT
  • Naringenin;Naringetol
  • $1.00 / 10g
  • 2022-02-25
  • CAS:480-41-1
  • Min. Order: 10g
  • Purity: 98% HPLC
  • Supply Ability: 1000kg
Naringenin Basic information
Pharmacological effects Application
Product Name:Naringenin
Synonyms:naringenine;naringetol;4’,5,7-trihydroxy-flavanon;S-Dihydrogenistein;NSC 34875;NSC 11855;(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-ben;4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-
CAS:480-41-1
MF:C15H12O5
MW:272.25
EINECS:207-550-2
Product Categories:Natural Plant Extract;natural product;chemical reagent;pharmaceutical intermediate;phytochemical;CITRIMORE;Flavanones;Inhibitors;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:480-41-1.mol
Naringenin Structure
Naringenin Chemical Properties
Melting point 247-250 °C(lit.)
Boiling point 335.31°C (rough estimate)
density 1.2066 (rough estimate)
FEMA 4797 | (+/-)-NARINGENIN
refractive index 1.6000 (estimate)
storage temp. Inert atmosphere,Room Temperature
form Powder
pka7.52±0.40(Predicted)
color Beige-brown
CAS DataBase Reference480-41-1(CAS DataBase Reference)
EPA Substance Registry System4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)- (480-41-1)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 26-36-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29329990
MSDS Information
Naringenin Usage And Synthesis
Pharmacological effectsNaringenin is the aglycone of naringin, it belongs to dihydro-flavonoids, at room temperature it is a white needle crystal(methanol), soluble in alcohol, ether and benzene, almost insoluble in water. In HCl-Mg powder reaction,it is cherry red ,in sodium borohydride reaction it is red purple, in molish reaction,it is negative. In the nature, it is mainly from the Rosaceae cherry (Prunus yedoensis Mate.) bud,and sumac plants (Amacardi-um occidentale L.)  fruits’ core-shell.
Nucleus structure is similar among flavonoids, most of the components do not have ideal fat-soluble and water-soluble abilities, the bioavailability is low. By modifying its structure, the introduction of strongly fat-soluble or water-soluble groups can increase its fat-soluble or water-soluble abilities, thus improving the bioavailability. The structure modification includes alkylation, acylation, sulfonation,glycosidation  of hydroxyl groups and the formation of the metal complex.
The effects of naringenin including: anti-bacterial, anti-inflammatory, antioxidant, cough expectorant,decreasing blood fat, anti-cancer and anti-tumor, antispasmodic, scavenging free radicals, prevention and treatment of liver disease, inhibition of platelet aggregation, anti-atherosclerosis and others , which can be widely used in medicine, food and other fields.
1. Antibacterial: it has a strong antibacterial effect on Staphylococcus aureus, Escherichia coli, Shigella dysenteriae, and Salmonella typhi. Naringenin also has effect on fungi  , 1000ppm is sprayed onto the rice, blast fungus infection can be reduced 40-90%,and it is not toxic to livestock and humans.
2. Anti-inflammatory: intraperitoneal injection of 20mg/kg per day for rats can inhibit the inflammatory process which caused by wool ball implantation.
3. Anticancer:  it displays action in L1210 leukemia and sarcomas in rats.
4. Antispasmodic and gallbladder: among the flavonoids,it has stronger effects. Naringenin has a strong effect on increasing bile secretion in experimental animals.
ApplicationIt has anti-bacterial, anti-inflammatory, anti-cancer, antispasmodic and choleretic effects.
Chemical Propertiesbeige-brown powder
UsesThe aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions
Usesantiulcer, antioxidant, immunomodulator, cholesterol lowering
Uses(S)-Naringenin, an active flavanone, maintains antioxidative, anti-inflammatory and antitumorigenic activities. Used in the treatment of praquat (PQ)-induced oxidative stress.
Purification MethodsCrystallise it from EtOH or aqueous EtOH. It has UV: at 290nm (EtOH). The S(-)-enantiomer (natural form) has m 255-256o (from EtOH) and [] D -28.0o (c 2, EtOH), [] D -35.2o (c 1, pyridine).
Naringenin Preparation Products And Raw materials
Tag:Naringenin(480-41-1) Related Product Information
Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) Naringin dihydrochalcone Naringin NARINGENIN CHALCONE,NARINGENIN CHALCONE NARINGENIN-7-O-GLUCOSIDE NARINGENIN (+/-)-Naringenin,(+/-)-Naringenin naringenin 7-O-methyltransferase,naringenin 7-O-methyltransferase 3,8”-Binaringenin -7”-o-β-glucoside NARINGENIN CHALCONE(RG),NARINGENIN CHALCONE(RG) NARINGENIN(P),NARINGENIN(P) Naringenin 4'-O-glucoside,Naringenin 4'-O-glucoside 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVANONE NARINGENIN 7-RHAMNOGLUCOSIDE HYDRATE,NARINGENIN 7-RHAMNOGLUCOSIDE HYDRATE 5,7-DIMETHOXY-4'-HYDROXYFLAVANONE (+/-)-TAXIFOLIN 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE TAXIFOLIN