AIDA manufacturers
- UPF-523
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- $3660.00 / 50mg
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2026-04-22
- CAS:168560-79-0
- Min. Order:
- Purity:
- Supply Ability: 10g
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| Product Name: | AIDA | | Synonyms: | 1-AMINO-2,3-DIHYDRO-1H-INDENE-1,5-DICARBOXYLIC ACID;(+/-)-1-AMINOINDAN-1,5-DICARBOXYLIC ACID;(+/-)-1-AMINOINDANE-1,5-DICARBOXYLIC ACID;AIDA;(RS)-1-AMINOINDAN-1,5-DICARBOXYLIC ACID;UPF 523;1-AMINOINDAN-1,5-DICARBOXYLIC ACID,UPF 5 23;(R,S)-1-Aminoindane-1,5-dicarboxylicacid | | CAS: | 168560-79-0 | | MF: | C11H11NO4 | | MW: | 221.21 | | EINECS: | | | Product Categories: | Glutamate receptor | | Mol File: | 168560-79-0.mol |  |
| Boiling point | 362.26°C (rough estimate) | | density | 1.2818 (rough estimate) | | refractive index | 1.5200 (estimate) | | storage temp. | 0-6°C | | solubility | DMSO: 2 mg/mL | | form | solid | | color | white | | InChI | 1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | | InChIKey | LSTPKMWNRWCNLS-UHFFFAOYSA-N | | SMILES | NC1(CCc2cc(ccc12)C(O)=O)C(O)=O |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 37/39-26 | | WGK Germany | 3 | | HS Code | 29224985 | | Storage Class | 11 - Combustible Solids |
| Chemical Properties | white to off-white powder | | Uses | AIDA is a potent and selective group I mGluR agonist. | | Biological Activity | A relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu 1a ), having no effect on group II (mGlu 2 ) or group III (mGlu 4 ) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutamate receptors. Centrally active following systemic administration in vivo . | | in vivo | UPF-523 (0.18 mg/kg; i.p.; 0.5 ml per 100 g) results in a final concentration of 100–150 mM which is below an IC50 of 214 mM[1]. | Animal Model: | Naive male hooded Lister rats (320–350 g)[1] | | Dosage: | 0.18 mg/kg | | Administration: | I.p.; 0.5 ml per 100 g | | Result: | Showed no gross motor abnormalities and normal righting reflexes.
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| | IC 50 | mGluR1a: 214 μM (IC50) | | storage | Store at RT |
| | AIDA Preparation Products And Raw materials |
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