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| | 3alpha-Akeboic acid Basic information |
| Product Name: | 3alpha-Akeboic acid | | Synonyms: | 3alpha-Akeboic acid;3alpha-Akebonoic acid;3-Epiakebonoic acid;(3alpha)-3-Hydroxy-30-noroleana-12,20(29)-dien-28-oic acid;30-Noroleana-12,20(29)-dien-28-oic acid, 3-hydroxy-, (3α)-;3α Akebonoic acid;3αAkebonoic acid;3α-Akebonoic Acid | | CAS: | 104777-61-9 | | MF: | C29H44O3 | | MW: | 440.65786 | | EINECS: | | | Product Categories: | | | Mol File: | 104777-61-9.mol |  |
| | 3alpha-Akeboic acid Chemical Properties |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder |
| | 3alpha-Akeboic acid Usage And Synthesis |
| Description | 3α-Akebonoic acid shows interesting in vitro growth inhibitory activity against human tumor A549 and HeLa cell lines, it also shows significant in vitro α-glucosidase inhibitory activity.
3α-Akebonoic acid can interfer with presenilin-1 (PS1)/ β-site APP-cleaving enzyme 1 (BACE1) interaction and reduces Aβ production, the chemical interference of PS1/BACE1 interaction is a promising strategy for Alzheimer’s disease therapeutics. | | target | Beta Amyloid | BACE |
| | 3alpha-Akeboic acid Preparation Products And Raw materials |
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