ChemicalBook > Product Catalog >Organic Chemistry >Amides >Amides >NG-25

NG-25

NG-25 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:NG25
CAS:1315355-93-1
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:HG-7-92-01
CAS:1315355-93-1
Purity:103599% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:NG-25
CAS:1315355-93-1
Purity:99.00% Package:25kgs/Drum;200kgs/Drum Remarks:ISO 9001:2015 REACH Approved Manufacturer
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:NG-25
CAS:1315355-93-1
Purity:98% Package:5mg Remarks:V4602
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:NG-25
CAS:1315355-93-1
Purity:98%+ HPLC Package:100MG,500MG,1G,5G,10G 50MG
NG-25 Basic information
Product Name:NG-25
Synonyms:N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide;3-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3v-(trifluoromethyl)phenyl)-4-methylbenzamide;NG-25;HG-7-92-01 (NG 25);N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide;NG 25; NG-25;Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-;NG-25 ISO 9001:2015 REACH
CAS:1315355-93-1
MF:C29H30F3N5O2
MW:537.58
EINECS:
Product Categories:Smad;TGF-beta;TGF-beta/Smad
Mol File:1315355-93-1.mol
NG-25 Structure
NG-25 Chemical Properties
density 1.313±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO
form powder
pka12.91±0.70(Predicted)
color white to beige
Safety Information
RIDADR UN 2811 6.1 / PGIII
MSDS Information
NG-25 Usage And Synthesis
UsesNG 25 inhibits TGF-beta-activated kinase 1 (TAK1). It also inhibits LYN, mitogen-activated protein kinase (MAP4K2) and Abl kinase activity.
Biochem/physiol ActionsNG25 is potent multiple kinase inhibitor belonging to type II kinase inhibitors class that binds to kinase ATP binding pocket at not ready to catalyze conformation. NG25 is used as a potent dual inhibitor of TAK1 (TGFβ-Activated Kinase 1, MAP3K7) and MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2; GCK) kinases. NG25 inhibits the activation of IKKa/IKKb and prevents the secretion of type 1 IFNs by TLR2 and TLR9 agonist.
storageStore at -20°C
NG-25 Preparation Products And Raw materials
Tag:NG-25(1315355-93-1) Related Product Information
Hydroxyethyl piperazine N-Ethylacetamide 2-Aminoethyl(ethyl)amine N-Ethyl-3-methylaniline N-ethyl-pyrrolidone N-(2-Hydroxyethyl)-2-pyrrolidone