- Acetyl pepstatin
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2026-10-19
- CAS:28575-34-0
- Min. Order: 1mg
- Purity: ≥95% or 98%
- Supply Ability: 1kg/month
- ACETYL-PEPSTATIN
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- $7.00
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2020-02-17
- CAS: 28575-34-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | ACETYL-PEPSTATIN Basic information |
| | ACETYL-PEPSTATIN Chemical Properties |
| storage temp. | −20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to Off-white | | InChIKey | WKYBEGDEGRCZNF-AHXZNPHMNA-N | | SMILES | [C@H](CC(C)C)([C@@H](O)CC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)C |&1:0,5,11,16,21,30,37,r| |
| WGK Germany | 3 | | HS Code | 2924190090 | | Storage Class | 11 - Combustible Solids |
| | ACETYL-PEPSTATIN Usage And Synthesis |
| Uses | Acetyl Pepstatin is an HIV-1 protease inhibitor. | | General Description | An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and HIV-2 proteinase (Ki = 5 nM at pH 4.7). | | Biochem/physiol Actions | Target Ki: 20 nM at pH 4.7 against HIV-1 proteinase | | in vivo | Pepstatin (Pepstatin A) has a very low toxicity, with LD50s of 1090 mg/kg, 875 mg/kg, 820 mg/kg and 450 mg/kg for mice, rats, rabbits, and dogs by i.p. route, and > 2000 mg/kg for all species by oral route[1].
Pepstatin (0.5-50 mg/kg, p.o.) suppresses stomach ulceration of the pylorus in ligated Shay rats[1]. | Animal Model: | Pylorus ligated male Wistar rats[1] | | Dosage: | 0.5, 1, 10 and 50 mg/kg | | Administration: | Oral administration, 15 minutes after pyloric ligation | | Result: | Effectively prevented stomach ulceration. |
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| | ACETYL-PEPSTATIN Preparation Products And Raw materials |
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