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ChemicalBook Optimization Suppliers |
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| 融点 | 195 °C | | 沸点 | 160℃/6mm | | 比重(密度) | 1.617±0.06 g/cm3(Predicted) | | 貯蔵温度 | Keep in dark place,Sealed in dry,Room Temperature | | 酸解離定数(Pka) | 16.43±0.30(Predicted) | | 外見 | Solid | | 色 | White | | 水溶解度 | Slightly soluble in water. | | InChIKey | LTBWKAYPXIIVPC-UHFFFAOYSA-N | | EPAの化学物質情報 | 3-Bromocarbazole (1592-95-6) |
| | 3-ブロモカルバゾール Usage And Synthesis |
| 外観 | 白色～うすい褐色、結晶性粉末～粉末 | | 化学的特性 | White to light yellow solid | | 使用 | 3-Bromo-9H-carbazole is an aryl hydrocarbon receptor agonist. A standard for environmental testing and research. Substance for the bological potency study, characterization of mono to tetra-halogenated carbazoles. | | 使用 | 3-Bromocarbazole is used as a intermediate for organic light-emitting diode(OLED) and pharmaceutical. | | 製造方法 | 3-Bromocarbazole synthesis: A solution of N-bromosuccinimide (1.1g, 5.98mmol) in dimethylformamide was added dropwise to a solution of carbazole (1, 1g, 5.96mmol) in dimethylformamide (15mL) at 0°C. The reaction mixture was then stirred at room temperature for 24h. The reaction was poured into distilled water to give a cream coloured precipitate. The precipitate was filtered off under vacuum and washed with distilled water (3 × 20mL). The precipitate was dissolved in ethyl acetate, dried with sodium sulfate and filtered. Upon concentration under reduced pressure the crude product was obtained as a brown solid. After crystallisation of the crude product with chloroform, the pure 3-Bromo-9H-carbazole(692 mg, 47%) was obtained as white crystals. Rf (ethyl acetate/hexane, 1:6 v/v): 0.43; melting point: 200–201°C. |
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