| 効能 | 抗緑内障薬, アセチルコリンエステラーゼ阻害薬 |
| 化学的特性 | Oily Liquid |
| 化学的特性 | Paraoxon is an odorless, reddish-yellow oil.
Fruity odor. |
| 使用 | Paraoxon-ethyl has been used as a substrate?in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein?L3 (HDL3)?to?HDL2?in vivo. |
| 使用 | Insecticide. |
| 使用 | A cholinesterase inhibitor |
| 定義 | ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl. |
| Synthesis Reference(s) | Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6 |
| 一般的な説明 | Reddish-yellow oily liquid with a faint fruity odor. |
| 反応プロフィール | Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. |
| 火災危険 | Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible. |
| Biochem/physiol Actions | Potent irreversible acetylcholinesterase inhibitor |
| 安全性プロファイル | A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos |
| 職業ばく露 | An organophosphate insecticide. Has
been used as a medication. |
| 輸送方法 | UN3018 Organophosphorus pesticides, liquid,
toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. |
| 不和合性 | Keep away from alkaline materials and
strong oxidizers. Contact with oxidizers can cause the
release of toxic oxides of phosphorus. May react violently
with antimony(V) pentafluoride. Incompatible with lead
diacetate, magnesium, silver nitrate. In the presence of
strong reducing agents such as hydrides, organophosphates
form highly toxic and flammable phosphine gas. |
| 廃棄物の処理 | In accordance with 40CFR165,
follow recommendations for the disposal of pesticides and
pesticide containers. Must be disposed properly by following
package label directions or by contacting your local or
federal environmental control agency, or by contacting
your regional EPA office. |