Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)

Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) Suppliers list
Company Name: BOC Sciences  
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Products Intro: Product Name:Ac-AAVALLPAVLLALLAP-DEVD-CHO trifluoroacetate salt
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Products Intro: Product Name:Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
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Products Intro: Product Name:Ac-AAVALLPAVLLALLAP-DEVD-CHO trifluoroacetate salt
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Products Intro: Product Name:Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) Basic information
Product Name:Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
Synonyms:Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) Structure
Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) Chemical Properties
solubility Formic Acid: 1 mg/ml
Safety Information
MSDS Information
Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) Usage And Synthesis
DescriptionAc-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO (Item No. 10017), a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF.1,2,3 It is an inhibitor of caspase-3 that reduces caspase-3 activity and apoptosis induced by prostaglandin E2 (PGE2; Item No. 14010) in rat cortical neurons when used at concentrations ranging from 1 to 2.5 μM.4WARNING This product is not for human or veterinary use.
References[1] M GARCIA-CALVO. Inhibition of human caspases by peptide-based and macromolecular inhibitors.[J]. The Journal of Biological Chemistry, 1998, 273 49: 32608-32613. DOI: 10.1074/jbc.273.49.32608
[2] R V TALANIAN. Substrate specificities of caspase family proteases.[J]. The Journal of Biological Chemistry, 1997, 272 15: 9677-9682. DOI: 10.1074/jbc.272.15.9677
[3] Y Z LIN. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence.[J]. The Journal of Biological Chemistry, 1995, 270 24: 14255-14258. DOI: 10.1074/jbc.270.24.14255
[4] TSUNEO TAKADERA. Prostaglandin E2 induces caspase-dependent apoptosis in rat cortical cells[J]. Neuroscience Letters, 2002, 317 2: Pages 61-64. DOI: 10.1016/s0304-3940(01)02449-1
Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) Preparation Products And Raw materials
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