伊维菌素B1B
| 中文名称 | 伊维菌素B1B |
|---|---|
| 中文同义词 | 伊维菌素B1B;伊维菌素杂质2;依维菌素B1B;伊维菌素H2B1B |
| 英文名称 | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- |
| 英文同义词 | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-;avermectin H2B1b;Component B1b;22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a;22,23-Dihydroavermectin B1b;Dihydroavermectin B1b;5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a |
| CAS号 | 70209-81-3 |
| 分子式 | C47H72O14 |
| 分子量 | 861.07 |
| EINECS号 | 274-384-5 |
| 相关类别 | 微生物代谢物 |
| Mol文件 | 70209-81-3.mol |
| 结构式 |  |
伊维菌素B1B 性质
| 沸点 | 934.1±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.24±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | DMF：可溶； DMSO：可溶；乙醇：可溶；甲醇：可溶 |
| 形态 | 固体 |
| 酸度系数(pKa) | 12.42±0.70(Predicted) |
| 颜色 | White to off-white |
| 稳定性 | 对温度敏感 |
| InChIKey | VARHUCVRRNANBD-PVVXTEPVSA-N |
Ivermectin B1b 是 Ivermectin 的次要成分。Ivermectin 是一种有效的抗寄生虫药物，可抑制 SARS-CoV-2 复制。
Ivermectin and Ivermectin B1b are the most potent inhibitors of contraction and motility in both susceptible isolates (
H. contortus
McMaster and and
O. circumcincta
McMaster) also show the highest resistance ratios in both species.
Vermectin is a macrocyclic lactone that acts as a positive allosteric modulator of α7 nicotinic acetylcholine receptors (nAChRs) but has no modulatory activity on 5-HT3 receptors.
Ivermectin B1b causes snail death.
安全信息
| 危险品运输编号 | 2588 |
|---|---|
| 危险等级 | 6.1(a) |
| 包装类别 | II |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/09/15 | HY-125729 | 伊维菌素B1B Ivermectin B1b | 70209-81-3 | 500μg | 2200元 |
| 2026/09/15 | HY-125729 | 伊维菌素B1B Ivermectin B1b | 70209-81-3 | 1 mg | 3520元 |