伊维菌素 B1A
| 中文名称 | 伊维菌素 B1A |
|---|---|
| 中文同义词 | 伊维菌素杂质1;依维菌素B1A;伊佛霉素B1A;伊维菌素H2B1A |
| 英文名称 | Avermectin A1a, 5-O-demethyl-22,23-dihydro- |
| 英文同义词 | 22,23-Dihydro-5-O-demethylavermectin A1a;5-O-Demethyl-22,23-dihydroavermectin A1a;Dihydroavermectin B1a;Ivermectin B1a;IvermectinH2B1a;(2Ae,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17ar,20R,20ar,20bs)-20,20B-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17A,20,20A,20B-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-L-arabino-hexopyranosyl)-3-o-methyl-alpha-L-arabino-hexopyranoside;Avermectin A1a, 5-O-demethyl-22,23-dihydro-;Ivermectin Impurity 3 |
| CAS号 | 71827-03-7 |
| 分子式 | C48H74O14 |
| 分子量 | 875.09 |
| EINECS号 | 276-046-2 |
| 相关类别 | 药物杂质及中间体;Organics |
| Mol文件 | 71827-03-7.mol |
| 结构式 |  |
伊维菌素 B1A 性质
| 熔点 | 155-157° |
|---|---|
| 沸点 | 717.97°C (rough estimate) |
| 密度 | 1.0683 (rough estimate) |
| 折射率 | 1.6130 (estimate) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 酸度系数(pKa) | 12.42±0.70(Predicted) |
| 颜色 | 白色 |
Ivermectin B1a 是 Avermectin B1a (HY-15308) 的衍生物，是 Ivermectin (HY-15310) 的主要成分。Ivermectin (MK-933) 是一种广谱抗寄生虫剂。Ivermectin 是应用于抗 SARS-CoV-2/COVID-19 的候选药物。
Ivermectin belongs to the macrocyclic lactone class of avermectins and consists of a mixture of two homologous compounds, ivermectin B1a (not less than 80%) and ivermectin B1b (not more than 20%). Ivermectin B1a, the major component of Ivermectin, is inactive at a concentration of 0.3 μg/ml, whereas in the case of the minor component, ivermectin B1b, the same concentration produces 100% mortality of snails.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-126937 | Ivermectin B1a | 1 mg | 1714元 | |
| 2024/04/30 | HY-126937 | 伊维菌素 B1A Ivermectin B1a | 71827-03-7 | 5mg | 4500元 |