Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-

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Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Suppliers list
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Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- manufacturers

  • FGFR3-IN-5
  • FGFR3-IN-5 pictures
  • $1980.00
  • 2026-07-27
  • CAS:2446664-72-6
  • Purity:
  • Supply Ability: 10g
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Basic information
Product Name:Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-
Synonyms:Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-;FGFR3-IN-5
CAS:2446664-72-6
MF:C24H24FN7O3
MW:477.49
EINECS:
Product Categories:
Mol File:2446664-72-6.mol
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Structure
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Chemical Properties
density 1.43±0.1 g/cm3(Predicted)
pka0.45±0.19(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Usage And Synthesis
UsesFGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1].
IC 50FGFR3: 3 nM (IC50); FGFR2: 44 nM (IC50); FGFR1: 289 nM (IC50)
References[1] James FB, et, al. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases. WO2020131627.
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Preparation Products And Raw materials
Tag:Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-(2446664-72-6) Related Product Information
FGFR-1 alpha (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-2 BETA (IIIB) Protein, HUMAN (HEK293, HIS) FGFR-3 beta (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-4 Protein, HUMAN (HEK293, HIS) Futibatinib Formononetin