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Formononetin

Formononetin Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Email: sales@capotchem.com
Products Intro: Product Name:Formononetin
CAS:485-72-3
Purity:98%(min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:Formononetin 485-72-3
CAS:485-72-3
Purity:99% Package:25KG;5KG;1KG
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
Tel: 025-83697070
Email: product@chemlin.com.cn
Products Intro: CAS:485-72-3
Purity:98% Package:g-Kg Remarks:White powder
Company Name: Nanjing Finetech Chemical Co., Ltd.
Tel: 025-85710122 17714198479
Email: sales@fine-chemtech.com
Products Intro: CAS:485-72-3
Purity:99%min Package:1KG;10KG;100KG;500KG;100g Remarks:ISO certified
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Formononetin
CAS:485-72-3
Purity:HPLC>=98% Package:20mg/200mg

Formononetin manufacturers

  • Formononetin
  • $13.66 / 1KG
  • 2022-02-25
  • CAS:485-72-3
  • Min. Order: 1Kg/Bag
  • Purity: 99%
  • Supply Ability: 20tons
  • Formononetin 485-72-3
  • $42.00 / 1g
  • 2022-02-14
  • CAS:485-72-3
  • Min. Order: 10mg
  • Purity: ≥98%
  • Supply Ability: 1000.00 kgs
  • Formononetin 485-72-3
  • $36.00 / 1g
  • 2022-02-14
  • CAS:485-72-3
  • Min. Order: 1g
  • Purity: ≥98%
  • Supply Ability: 1000.00 kgs
Formononetin Basic information
Product Name:Formononetin
Synonyms:Formononetin (50 mg);red clover extract_formononetin;Flavosil;ForMonentin;Myconate;NSC 93360;ForMononetin (ForMononetol);ForMoononetin
CAS:485-72-3
MF:C16H12O4
MW:268.26
EINECS:207-623-9
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Iso-Flavones;The group of Astralosides;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors
Mol File:485-72-3.mol
Formononetin Structure
Formononetin Chemical Properties
Melting point 256-260 °C
Boiling point 331.43°C (rough estimate)
density 1.1529 (rough estimate)
refractive index 1.4350 (estimate)
storage temp. 2-8°C
solubility Soluble in DMSO (up to 100 mg/ml).
pka6.99±0.20(Predicted)
form Powder
color White to light beige
λmax300nm(EtOH)(lit.)
Merck 14,4244
BRN 237979
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKeyHKQYGTCOTHHOMP-UHFFFAOYSA-N
CAS DataBase Reference485-72-3(CAS DataBase Reference)
EPA Substance Registry System4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)- (485-72-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26-36
WGK Germany 3
RTECS DJ3100114
HS Code 29329990
MSDS Information
ProviderLanguage
7-Hydroxy-3-(4-methoxyphenyl)chromone English
ACROS English
Formononetin Usage And Synthesis
DescriptionFormononetin (485-72-3) is a naturally occurring isoflavone isolated from Astragalus and other plants. Increases adipocyte thermogenesis by modulating PPARγ activity.1?Activates AMP-activated protein kinase/β-catenin signaling to inhibit adipogenesis.2?Accelerates wound repair by increasing expression of Egr-1 transcription factor.3?Potential cancer chemopreventive and chemotherapeutic.4?Provides neuroprotection against traumatic brain injury by inhibition of neuroinflammation in a rat model.5
Chemical Propertiesoff-white powder
UsesFormononetin is an isoflavone found as one of the main plant estrogens in animal feed. When metabolized in the rumen this compound transforms into a potent estrogen.
Usesphytoestrogen
UsesAn isoflavone found in a variety of plants. When metabolized in the rumen this compound transforms into a potent estrogen.
UsesFormononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein . It acts as an agonist of the aryl hydrocarbon receptor with an EC50 value of 0.13 μM. Formononetin has been reported to possess antitumor and antiviral activity.
General Description
Formononetin belongs to the isoflavones class of polyphenols.
Biochem/physiol ActionsIsoflavone found in red clover. Effective against Giardia lamblia infection, at least partially by inducing detachment of trophozoites from intestinal mucosa.
References1) Nie?et al.?(2018),?The natural compound, formononetin, extracted from Astragalus membranaceus increases adipocyte thermogenesis by modulating PPARγ activity; Br. J. Pharmacol.,?175?1439 2) Gautam?et al.?(2017),?Formononetin, an isoflavone, activates AMO-activated protein kinase/?β-catenin signaling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss; Br. J. Nutrit.,?117?645 3) Huh?et al. (2011),?Formononetin accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERK and p38 MAPK pathways; Int. Immunopharmacol.,?11?46 4) Ong?et al.?(2019),?Focus on Formononetin: Anticancer Potential and Molecular Targets; Cancers (Basel),?11?E611 5) Li?et al.?(2018),?Neuroprotective effect of formononetin against TBI in rats via suppressing inflammatory reaction in cortical neurons; Biomed. Pharmacother.,?106?349
Tag:Formononetin(485-72-3) Related Product Information
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