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Cyanine7 carboxylic acid

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Cyanine7 carboxylic acid manufacturers

Cyanine7 carboxylic acid Basic information
Product Name:Cyanine7 carboxylic acid
Synonyms:Cyanine7 carboxylic acid;Cyanine7-COOH;lipo Cy7(Me);6-[(Z)-3,3-dimethyl-2-[(2E,4E,6E)-7-(1,3,3-trimethyl-3H-indol-1-ium-2-yl)hepta-2,4,6-trien-1-ylidene]indolin-1-yl]hexanoate;6-(3,3-Dimethyl-2-(7-(1,3,3-trimethyl-3H-indol-1-ium-2-YL)hepta-2,4,6-trien-1-ylidene)indolin-1-YL)hexanoate;Cy7-M Free Acid (NIR);1-(3-amino-3-deoxy-β-D-arabinofuranosyl)thymine;TJ-Cy7-COOH
CAS:1144107-78-7
MF:C34H40N2O2
MW:508.71
EINECS:
Product Categories:
Mol File:1144107-78-7.mol
Cyanine7 carboxylic acid Structure
Cyanine7 carboxylic acid Chemical Properties
solubility Soluble in organic solvents such as DMF
AppearanceGreen solid
ex/em740/770 nm (MeOH/PBS)
ε(extinction coefficient)199000 L⋅mol−1⋅cm−1
Φ(quantum yield)0.3
InChIKeyMQMHUMKZLAOASA-UHFFFAOYSA-N
SMILESC(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC=CC=CC1C(C2=CC=CC=C2[N+]=1C)(C)C)CCCCC(=O)[O-]
Safety Information
MSDS Information
Cyanine7 carboxylic acid Usage And Synthesis
Description

The unactivated free carboxylic acid of near-infrared fluorescent dye Cyanine7. For coupling and labeling reactions also consider using pre-activated Cyanine7 NHS ester, or water-soluble sulfo-Cyanine7 NHS ester.

Chemical PropertiesAppearance: Green solid
ex/em: 740/770 nm (MeOH/PBS)
Extinction coefficient (ε): 199000 Lmol1cm1
Quantum yield (Φ): 0.3
UsesCyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds[1].
References[1] Zhang X, et al. Highly stable near-infrared dye conjugated cerasomes for fluorescence imaging-guided synergistic chemo-photothermal therapy of colorectal cancer. Biomater Sci. 2019 Jul 1;7(7):2873-2888. DOI:10.1039/c9bm00458k
Abs/Em Maxima750/773 nm
Extinction Coefficient199000
CF2600.022
CF2800.029
Cyanine7 carboxylic acid Preparation Products And Raw materials
Tag:Cyanine7 carboxylic acid(1144107-78-7) Related Product Information
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