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CHEMAZON LABORATORIES
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+91 9848551964 |
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Info@chemazonlabs.com |
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Product Name:Propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2- [(E,3R)-3-hydroxy-5-phenylpent-1- enyl]cyclopentyl]hept-5-enoate CAS:130273-87-9 Purity:98% Package:100 mg, 1 g, 100 g and 1 kg
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Chemicea Pharmaceuticals Pvt Ltd
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+91-918482849343 +91-8482849343 |
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Product Name:Bimatoprost isopropyl ester CAS:130273-87-9 Purity:99% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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Company Name: |
OPULENT PHARMA
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+91-9106692785 +91-9106692785 |
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Product Name:Bimatoprost isopropyl ester CAS:130273-87-9 Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER Basic information |
Product Name: | 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER | Synonyms: | 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER;15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester;15(R)-Bimatoprost isopropyl ester;9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER;JGZRPRSJSQLFBO-DYZSFVSISA-N;15-epi Bimatoprost isopropyl ester;BIMATOPROST ISOPROPYL ESTER/7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-[(1E,3R)-3-HYDROXY-5-PHENYL-1-PENTEN-1-;Bimatoprost Isopropyl Ester/7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-5-Phenyl-1-Penten-1-Yl]Cyclopentyl]-(5Z)-5-Heptenoic Acid 1-Methylethyl Ester | CAS: | 130273-87-9 | MF: | C26H38O5 | MW: | 430.58 | EINECS: | | Product Categories: | | Mol File: | 130273-87-9.mol | |
| 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER Chemical Properties |
storage temp. | Store at -20°C | solubility | DMF:30.0(Max Conc. mg/mL);69.67(Max Conc. mM) Ethanol:30.0(Max Conc. mg/mL);69.67(Max Conc. mM) PBS (pH 7.2):1.0(Max Conc. mg/mL);2.32(Max Conc. mM) |
| 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER Usage And Synthesis |
Description | 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys. |
| 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER Preparation Products And Raw materials |
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