| Company Name: |
Clearsynth Labs Limited
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| Tel: |
+91-22-26355700 |
| Email: |
info@clearsynth.com |
| Products Intro: |
Product Name:7a-Hydroxycholesterol-d7
CAS:349553-94-2
Remarks:CS-C-01443
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| Company Name: |
ChemStrong Scientific Co.,Ltd
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| Tel: |
0755-0755-66853366 13670046396 |
| Email: |
sales@chem-strong.com |
| Products Intro: |
Product Name:Cholesterol Impurity 37
CAS:349553-94-2
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:7alpha-hydroxycholesterol (D7)
CAS:349553-94-2
Purity:cholest-5-en-3beta,7alpha-diol(d7), methanol solution Package:1EA Remarks:LM4103-1EA
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| Company Name: |
Codow Chemical Co.,Ltd.
|
| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:cholest-5-en-3?,7α-diol-d7
CAS:349553-94-2
Purity:>99% Package:1MG
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| | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Basic information |
| Product Name: | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 | | Synonyms: | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7;cholest-5-en-3,7α-diol-d7;CHOLEST-5-EN-3,7Α-DIOL-D7;7Α-HYDROXYCHOLESTEROL-D7;7alpha-hydroxycholesterol-d7;7α-hydroxy Cholesterol-d7;7α-Hydroxycholesterol-25?26?26?26?27?27?27-[d7];Cholesterol Impurity 37;cholest-5-en-3?,7α-diol-d7 | | CAS: | 349553-94-2 | | MF: | C26H37D7O2 | | MW: | 395.67 | | EINECS: | | | Product Categories: | Hydroxycholesterol | | Mol File: | 349553-94-2.mol |  |
| | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Chemical Properties |
| storage temp. | -20°C | | solubility | DMF: 2 mg/ml; DMSO: 0.1 mg/ml; Ethanol: 20 mg/ml | | form | A solid |
| | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Usage And Synthesis |
| Description | 7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS. 7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid (CA; ) and chenodeoxycholic acid (CDCA; ). It is formed via the oxidation of cholesterol by cholesterol 7α-hydroxylase/CYP7A1 in rat liver microsomes. 7α-hydroxy Cholesterol (40 μM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). It increases secretion of chemokine (C-C motif) ligand 2 (CCL2) and matrix metalloproteinase-9 (MMP-9) in serum-deprived THP-1 cells when used at a concentration of 5 μg/ml. 7α-hydroxy Cholesterol has been found in macrophages isolated from atherosclerotic lesions in rabbits fed a high-cholesterol diet. | | Uses | 7α-hydroxycholesterol-d7 has been used as an internal standard for cholesterol and oxysterol measurement by gas chromatography-mass spectrometry (GC/MS). | | General Description | 7α-hydroxycholesterol is an oxysterol synthesized by the oxidation of the side chain of cholesterol. It is the precursor of bile acid. |
| | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Preparation Products And Raw materials |
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