| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:(R)-(+)-8-Hydroxy-DPAT hydrobromide
CAS:78095-19-9
Purity:>=98% (HPLC), solid Package:100MG Remarks:H140-100MG
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| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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| Tel: |
021-65675885 18964387627 |
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info@efebio.com |
| Products Intro: |
Product Name:(R)-(+)-8-Hydroxy-DPAT hydrobromide
CAS:78095-19-9
Purity:98% Package:5mg;10mg;25mg
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| Company Name: |
BOC Sciences
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info@bocsci.com |
| Products Intro: |
Product Name:(R)-(+)-8-Hydroxy-DPAT hydrobromide
CAS:78095-19-9
Purity:≥99% by HPLC Remarks:(R)-(+)-8-Hydroxy-DPAT hydrobromide is a full 5-HT1A serotonin receptor agonist. It decreases hippocampal 5-HT levels following systemic administration in rats in vivo.
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| | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Basic information |
| Product Name: | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE | | Synonyms: | R(+)-8-HYDROXY-DPAT HYDROBROMIDE FULL 5- HT1A SEROTONIN;(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide;(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide;Hydroxy-DPAT hydrobromide, (R)-(+)-8-;(R) (+) 8 Hydroxy DPAT hydrobromide,(R)(+)8HydroxyDPAT hydrobromide | | CAS: | 78095-19-9 | | MF: | C16H25NO.BrH | | MW: | 328.291 | | EINECS: | | | Product Categories: | | | Mol File: | 78095-19-9.mol |  |
| | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Chemical Properties |
| storage temp. | protect from light | | solubility | H2O: >10mg/mL at ±60°C (with sonication) | | form | solid | | color | white to off-white | | optical activity | [α]25/D +68.2°, c = 1 in methanol(lit.) |
| | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Usage And Synthesis |
| Uses | (R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:
- in mice to test the activity of the serotonin receptor
- to test its effect on zebrafish melanocyte migration and survival
- to stimulate hippocampal neurons
| | Biochem/physiol Actions | (R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation. | | storage | Desiccate at +4°C |
| | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Preparation Products And Raw materials |
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