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ATP synthase inhibitor 1 manufacturers
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| | ATP synthase inhibitor 1 Basic information |
| Product Name: | ATP synthase inhibitor 1 | | Synonyms: | ATP SYNTHASE INHIBITOR 1;ATP Synthase,ATP synthase inhibitor 1,Inhibitor,inhibit,ATP synthase inhibitor-1,ATP synthase inhibitor1;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(5-chloro-2-thienyl)sulfonyl]-1-phenyl-;8-((5-Chlorothiophen-2-yl)sulfonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | | CAS: | 1023043-30-2 | | MF: | C17H18ClN3O3S2 | | MW: | 411.93 | | EINECS: | | | Product Categories: | | | Mol File: | 1023043-30-2.mol |  |
| | ATP synthase inhibitor 1 Chemical Properties |
| density | 1.55±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C,unstable in solution, ready to use. | | solubility | DMSO: 5 mg/mL (12.14 mM) | | pka | 14.80±0.20(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | ATP synthase inhibitor 1 Usage And Synthesis |
| Description | ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1].
F1/FO-ATP synthase[1] ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex[1]. | | Uses | ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1]. | | References | [1]. Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61(16):7131-7143. |
| | ATP synthase inhibitor 1 Preparation Products And Raw materials |
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