ブロマジオロン(28772-56-7)

ブロマジオロン 製品概要
化学名:ブロマジオロン
英語化学名:Bromadiolone
别名:(hydroxy-4coumarinyl3)-3phenyl-3(bromo-4biphenylyl-4)-1propanol-1;(hydroxy-4-coumarinyl-3)-3-phenyl-3-(bromo-4-biphenylyl-4)-1-propanol-1(french;1’-biphenyl)-4-yl)3-hydroxy-1-phenylpropyl)-4-hydroxy-2h-1-3-(3-(4’-bromo(;2h-1-benzopyran-2-one,3-(3-(4`-bromo-(1,1`-biphenyl)-4-yl)-3-hydroxy-1-phenylp;2h-1-benzopyran-2-one,3-(3-(4’-bromo(1,1’-biphenyl)-4-yl)-3-hydroxy-1-phenylp;SUPER-ROZOL;SUPER CAID;RATOBAN
CAS番号:28772-56-7
分子式:C30H23BrO4
分子量:527.41
EINECS:249-205-9
カテゴリ情報:Alphabetic;S;SN - SZ;INSECTICIDE
Mol File:28772-56-7.mol
ブロマジオロン
ブロマジオロン 物理性質
融点 200-210°
沸点 723.4±60.0 °C(Predicted)
比重(密度) 1.3243 (rough estimate)
蒸気圧2 x l0-6Pa (20 °C)
屈折率 1.4490 (estimate)
貯蔵温度 -20°C
溶解性DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
水溶解度 19 mg l-1 (20 °C)
外見 Powder
酸解離定数(Pka)4.04(at 21℃)
Merck 13,1366
BRN 1335336
LogP7.480 (est)
CAS データベース28772-56-7(CAS DataBase Reference)
EPAの化学物質情報Bromadiolone (28772-56-7)
安全性情報
主な危険性 T+,N
Rフレーズ 27/28-50
Sフレーズ 28-36/37/39-45-61
RIDADR UN 2811
WGK Germany 3
RTECS 番号GN4934700
国連危険物分類 6.1(a)
容器等級 I
有毒物質データの28772-56-7(Hazardous Substances Data)
毒性LD50 in rats, mice (mg/kg): 1.125, 1.75 orally (Grand)
MSDS Information
ProviderLanguage
Bromadiolone English
ブロマジオロン Usage And Synthesis
説明Bromadiolone is used to control rodents around buildings, inside transport vehicles and sewers. It is often formulated as meal bait, rat and mouse bait ready-to-use place packs, paraffinized pellets and blocks.
化学的特性Bromadiolone is white to off-white (yellowish) powder.
天然物の起源Boldo is an evergreen found in Chile, Peru, and Morocco.
使用Bromadiolone is used for the control of rats and mice.
使用Rodenticide.
使用Bromadiolone is an anticoagulant rodenticide used on non-crop areas.
定義ChEBI: Bromadiolone is a diarylheptanoid.
一般的な説明Yellowish powder. Used as an anticoagulant rodenticide.
健康ハザードThe compound is toxic by oral exposure.
火災危険(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, Bromadiolone emits toxic fumes of bromine containing compounds.
农业用途Rodenticide: Bromadiolone is used as an anticoagulant rodenticide and used as bait for rodent control against house mice, roof rats and warfarin-resistant Norway rats. It is also authorized by USDA for use in official establishments operating under the Federal meat, poultry, shell egg grading and egg products inspection program.
製品名BOLDO®; BOOT HILL®; BROMONE®; CANADIEN 2000®; CONTRAC®; HAWK®; LM- 637®; MAKI®; RAT ARREST®; RAT FREE®; RATIMUS®; RENTOKIL DEADLINE®; SLAYMOR®; SUPER-CAID®; SUPER-ROZOL®; SUP'ORATS®; TERMUS®
職業ばく露Bromadiolone is used as an anticoagulant rodenticide. It is bait for rodent control used against house mice, roof rats, warfarin-resistant Norway rats. It is also authorized by USDA for use in official establishments operating under the federal meat, poultry, shell egg grading, and egg products inspection program. May be used as a drug.
応急処置If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit. Keepvictim quiet and maintain normal body temperature. Effectsmay be delayed; keep victim under observation.
環境運命予測Bromadiolone belongs to second generation of long-acting anticoagulant rodenticide. It acts by interfering with the prothrombin synthesis by blocking the regeneration of vitamin K dependant proteins in the liver and thereby disrupting the clotting mechanisms and increasing the tendency to hemorrhages and subsequent death.
代謝経路Metabolism in the rat is very slow and products other than a conjugate of the parent compound have not been identified. Biodegradation in soil and plants has not been reported.
貯蔵Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with bromadiolone you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area.
輸送方法UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials. UN3026 Coumarin derivative pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials.
Toxicity evaluationBromadiolone may be released into the environment through various waste streams and its use. If released to air, it will exist in the particulate phase in the ambient atmosphere and will be removed by dry and wet deposition. In soil, it is not persistent under aerobic conditions (half-life is 14 days) and is usually immobile except in soils of low organic matter and clay, such as sand.
When released to water, it adsorbs to suspended solids and sediment. Bromadiolone is stable to hydrolysis at pH 5, 7, and 9. Two major degradates, [1,3-diphenyl-5(40-bromobiphenyl) pentane-1-ol] and [1,3-diphenyl-5(40-bromobiphenyl) pentane-1,5-diol], are detected in the aerobic soil metabolism study.
Bromadiolone is bioaccumulated in edible and nonedible tissues in bluegill sunfish at the bioaccumulation concentration factors of 160X and 1658X. It was also detected in birds.
DegradationBromadiolone is a stable compound. It is a weak acid.
Tags:28772-56-7