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ChemicalBook Optimization Suppliers |
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| 化学名: | ダルババンシン | | 英語化学名: | Dalbavancin | | 别名: | Dalbavancin;MDL 63397;A-A-1, Dalbavancin Ao, BI 397, MDL 63397;Dalbavancin(BI 397, MDL 63397);CS-2250;Dalbavancin Ao;Dalbavancin(BI 397;DALBAVANCIN;MDL 63397;A-A-1; DALBAVANCIN AO; BI 397; MDL 63397;DALBAVANCIN(BI 397; MDL 63397) | | CAS番号: | 171500-79-1 | | 分子式: | C88H100Cl2N10O28 | | 分子量: | 1816.71 | | EINECS: | 206-141-6 | | カテゴリ情報: | | | Mol File: | 171500-79-1.mol |  |
| 融点 | >160°C (dec.) | | 比重(密度) | 1.59 | | 貯蔵温度 | -20°C | | 溶解性 | Aqueous Base (Slightly), DMSO (Slightly, Heated), Water (Slightly) | | 酸解離定数(Pka) | 2.73±0.70(Predicted) | | 外見 | powder | | 色 | white to beige |
| | ダルババンシン Usage And Synthesis |
| 効能 | 抗生物質, 細胞壁合成阻害薬 | | 使用 | Dalbavancin is a second-generation lipoglycopeptide antibiotic. It is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available, vancomycin and teicoplanin. | | 使用 | Dalbavancin is a semi-synthetic glycopeptide prepared from A40926 by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in vitro activity against a variety of Gram positive and multi-drug resistant isolates such as MRSA and MRSE. | | 定義 | ChEBI: A semisynthetic glycopeptide used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. |
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