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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
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Product Name:15(S)-HETrE
CAS:92693-02-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
BOC Sciences
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info@bocsci.com |
| Products Intro: |
Product Name:15(S)-HETrE
CAS:92693-02-2
Purity:≥98% Remarks:15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM.
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:15(S)-HETrE
CAS:92693-02-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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021-69568360 18916172912 |
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order@med-bio.cn |
| Products Intro: |
Product Name:15(S)-HETRE
CAS:92693-02-2
Purity:98% Package:50ug (solution); 25ug (solution); 100ug (solution); 500ug (solution) Remarks:Medbio
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| | 15(S)-HETRE Basic information |
| Product Name: | 15(S)-HETRE | | Synonyms: | 15(S)-HETRE;15S-HYDROXY-8Z,11Z,13E-EICOSATRIENOIC ACID;15(S)-HYDROXYEICOSA-8Z, 11Z, 13E-TRIENOIC ACID;IUKXMNDGTWTNTP-OAHXIXLCSA-N;15(S) HETrE,15(S)HETrE;8,11,13-Eicosatrienoic acid, 15-hydroxy-, (8Z,11Z,13E,15S)- | | CAS: | 92693-02-2 | | MF: | C20H34O3 | | MW: | 322.48 | | EINECS: | | | Product Categories: | | | Mol File: | 92693-02-2.mol |  |
| | 15(S)-HETRE Chemical Properties |
| Boiling point | 487.4±40.0 °C(Predicted) | | density | 0.971±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | | pka | 4.77±0.10(Predicted) |
| | 15(S)-HETRE Usage And Synthesis |
| Description | 15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; ). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM.1 In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.2 | | References | 1. Petrich, K., Ludwig, P., Kühn, H., et al. The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leukocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: Structure-activity relationship and mechanism of action Biochem. J. 314,911-916(1996).
2. Haviv, F., Ratajczyk, J.D., DeNet, R.W., et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues J. Med. Chem. 30(2),254-263(1987). |
| | 15(S)-HETRE Preparation Products And Raw materials |
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