|
|
| | 6-Aminooxy-hexanoic acid Basic information |
| Product Name: | 6-Aminooxy-hexanoic acid | | Synonyms: | 6-Aminooxy-hexanoic acid;6-Aminooxy-hexanoic acid,hydrobromide;6-Aminooxy-hexamoic acid hydrobromide;HBr.H2N-O-(CH2)5-COOH;hydrobromide, 10 mg;hydrobromide, 100 mg;NH2-O-C5-COOH hydrobromide;6-Aminooxy-hexanoic acid, HBr | | CAS: | 448954-98-1 | | MF: | C6H13NO3.BrH | | MW: | 228.09 | | EINECS: | | | Product Categories: | | | Mol File: | 448954-98-1.mol |  |
| | 6-Aminooxy-hexanoic acid Chemical Properties |
| | 6-Aminooxy-hexanoic acid Usage And Synthesis |
| Biological Activity | NH2-O-C5-COOH (hydrobromide) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 6-Aminooxy-hexanoic acid Preparation Products And Raw materials |
|