| Company Name: |
Varanous Labs Pvt Ltd
|
| Tel: |
+91-7036248882 +91-7036248882 |
| Email: |
bheemashankar.e@varanouslabs.com |
| Products Intro: |
Product Name:Melagatran
CAS:159776-70-2
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
|
|
| | Melagatran Basic information |
| Product Name: | Melagatran | | Synonyms: | H-319/68;Melagatran;N-[(1R)-2-[(2S)-2-[[[[4-(Aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]glycine;2-(((R)-2-((S)-2-((4-Carbamimidoylbenzyl)carbamoyl)azetidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)acetic acid;2-[[(1R)-2-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]azetidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]acetic acid;Glycine, N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]- | | CAS: | 159776-70-2 | | MF: | C22H31N5O4 | | MW: | 429.51 | | EINECS: | | | Product Categories: | Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics Compounds | | Mol File: | 159776-70-2.mol |  |
| | Melagatran Chemical Properties |
| Melting point | 198-200°C | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 2.12±0.10(Predicted) | | color | White to Off-White | | Stability: | Hygroscopic |
| | Melagatran Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic. | | Definition | ChEBI: Melagatran is a member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. It has a role as an anticoagulant, an EC 3.4.21.5 (thrombin) inhibitor and a serine protease inhibitor. It is a carboxamidine, a dicarboxylic acid monoamide, a non-proteinogenic alpha-amino acid, a secondary amino compound and a member of azetidines. |
| | Melagatran Preparation Products And Raw materials |
|