| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Cytochrome c
Purity:~ 0.5mg/mL, affinity isolated antibody, buffered aqueous sol Package:200μL Remarks:C9616
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:whole antiserum Remarks:~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution
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| Company Name: |
R & D Systems
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| Tel: |
612 379 2956 |
| Email: |
info@rndsystems.com |
| Products Intro: |
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| Company Name: |
AnaSpec, Inc.
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| Tel: |
800 452 5530 |
| Email: |
service@anaspec.com |
| Products Intro: |
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| | ANTI-CYTOCHROME C Basic information |
| Product Name: | ANTI-CYTOCHROME C | | Synonyms: | ANTI-APAF-2 (AB-1), RABBIT;ANTI-APAF-2 (AB-1) SHEEP PAB;ANTI-APAF-2 (AB-2), MAMMALIAN;ANTI-HUMAN CYTOCHROME C;ANTI-HUMAN/MOUSE/RAT CYTOCHROME C;ANTI-CYTOCHROME C(H-104);ANTI-CYTOCHROME C MAB;ANTI-CYTOCHROME C MOUSE MAB | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-CYTOCHROME C Structure]() |
| | ANTI-CYTOCHROME C Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-CYTOCHROME C Usage And Synthesis |
| Uses | Anti-Cytochrome c antibody produced in sheep has been used in:
- immunocytochemistry
- immunostaining
- immunoblotting
- immunohistochemistry
| | General Description | Anti-Cytochrome c produced in sheep using purified rabbit cytochrome c conjugated to keyhole limpet hemocyanin (KLH). | | Biochem/physiol Actions | Cytochrome c controls cellular electron transport and energy metabolism. It is involved in the transfer of electrons between complex III and complex IV in the mitochondrial electron transport chain. It is involved in apoptosis and activates the death protease caspase-3 (CCP32). The presence of Bcl-2 on the organelles inhibits the release of cytochrome c from mitochondria during apoptosis. Along with Apaf-1, and procaspase-9, it forms an essential component of vertebrate ”apoptosome”. Activation of caspase-9 and other capsases directs apoptosis. Serum cytochrome c is a sensitive apoptotic marker in vivo, and increased serum cytochrome c level can serve as a negative prognostic marker. |
| | ANTI-CYTOCHROME C Preparation Products And Raw materials |
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