| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:16-phenyl tetranor Prostaglandin E2
CAS:38315-44-5
Package:>99% Remarks:14770
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| | 16-PHENYL TETRANOR PROSTAGLANDIN E2 Basic information |
| Product Name: | 16-PHENYL TETRANOR PROSTAGLANDIN E2 | | Synonyms: | 9-OXO-11ALPHA-15S-DIHYDROXY-16-PHENYL-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;16-PHENYL TETRANOR PROSTAGLANDIN E2;DXWJXQSQVUJRNS-YYWARMNLSA-N;5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)- | | CAS: | 38315-44-5 | | MF: | C22H28O5 | | MW: | 372.45 | | EINECS: | | | Product Categories: | | | Mol File: | 38315-44-5.mol |  |
| | 16-PHENYL TETRANOR PROSTAGLANDIN E2 Chemical Properties |
| Boiling point | 576.8±50.0 °C(Predicted) | | density | 1.235±0.06 g/cm3(Predicted) | | solubility | DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml | | pka | 4.75±0.10(Predicted) |
| | 16-PHENYL TETRANOR PROSTAGLANDIN E2 Usage And Synthesis |
| Description | 16-phenyl tetranor PGE2 is a metabolically stable synthetic analog of PGE2. 16-phenyl tetranor PGE2 is five times more potent than PGE2 in causing hypotension in dogs (0.1 μg/kg dose).1 It is comparable to PGE2 in inhibiting histamine-induced bronchoconstriction in conscious guinea pigs.1 | | Definition | ChEBI: 16-Phenyl-tetranor-PGE2 is a prostanoid. | | References | 1. Johnson, M.R., Schaaf, T.K., Constantine, J.W., et al. Structure activity studies leading to a tissue-selective hypotensive prostaglandin analog, 13,14-dihydro-16-phenyl-ω-tetranor PGE2 Prostaglandins 20(3),515-520(1980). |
| | 16-PHENYL TETRANOR PROSTAGLANDIN E2 Preparation Products And Raw materials |
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