| Company Name: |
Lynnchem
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| Tel: |
86-(0)29-85992781 17792393971 |
| Email: |
info@lynnchem.com |
| Products Intro: |
Product Name:marcfortine A
CAS:75731-43-0
Purity:>99% by HPLC Package:1mg;5mg
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| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Email: |
info@novachemistry.com |
| Products Intro: |
Product Name:Marcfortine A
CAS:75731-43-0
Purity:>99% by HPLC Package:1mg;5mg
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| | marcfortine A Basic information |
| Product Name: | marcfortine A | | Synonyms: | marcfortine A;UK 111866;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)- | | CAS: | 75731-43-0 | | MF: | C28H35N3O4 | | MW: | 477.602 | | EINECS: | | | Product Categories: | | | Mol File: | 75731-43-0.mol |  |
| | marcfortine A Chemical Properties |
| Melting point | 245 °C | | Boiling point | 660.6±55.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Methanol: soluble | | form | A solid | | pka | 12.05±0.60(Predicted) |
| | marcfortine A Usage And Synthesis |
| Description | Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively. | | Uses | Marcfortine A is an indole alkaloid isolated from Aspergillus and Pencillium species. | | Uses | Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission. |
| | marcfortine A Preparation Products And Raw materials |
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