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ChemicalBook Optimization Suppliers |
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| | (20R,22R)-2β,3β,14,20,22-ペンタヒドロキシ-5β-コレスタ-7-エン-6-オン 製品概要 |
| 化学名: | (20R,22R)-2β,3β,14,20,22-ペンタヒドロキシ-5β-コレスタ-7-エン-6-オン | | 英語化学名: | Ponesterone A | | 别名: | 2β,3β,14α,20r,22r-pentahydroxy-5β-cholest-7-en-6-one;2B,3B,14A,20R,22R-PENTAHYDROXY-5B-CHOLEST-7-EN-6-ONE;2BETA, 3BETA, 14ALPHA, 20R,22R-PENTAHYDROXY-5BETA-CHOLEST-7-EN-6-ONE;25-DEOXY-20-HYDROXYECDYSONE;25-DEOXYECDYSTERONE;Ponasterone A, >=98%;25-Deoxy-20-hydroxyecdysone, 25-Deoxyecdysterone, 2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one;(20R,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7-ene-6-one | | CAS番号: | 13408-56-5 | | 分子式: | C27H44O6 | | 分子量: | 464.63 | | EINECS: | | | カテゴリ情報: | Steroids | | Mol File: | 13408-56-5.mol |  |
| | (20R,22R)-2β,3β,14,20,22-ペンタヒドロキシ-5β-コレスタ-7-エン-6-オン 物理性質 |
| 融点 | 259-260° (dec) | | 比旋光度 | D15 +90° (methanol) | | 沸点 | 640.5±55.0 °C(Predicted) | | 比重(密度) | 1.22±0.1 g/cm3(Predicted) | | 貯蔵温度 | −20°C | | 溶解性 | Methanol (Slightly, Sonicated), Pyridine (Slightly) | | 酸解離定数(Pka) | 14.13±0.70(Predicted) | | 外見 | White to off-white powder. | | 色 | White to Off-White | | InChIKey | PJYYBCXMCWDUAZ-JJJZTNILSA-N | | CAS データベース | 13408-56-5(CAS DataBase Reference) |
| | (20R,22R)-2β,3β,14,20,22-ペンタヒドロキシ-5β-コレスタ-7-エン-6-オン Usage And Synthesis |
| 説明 | Ponesterone A, a steroidal compound, falls under the category of ecdysone and can be found in various sources throughout nature. It was first isolated from insect plants by Nakanishi and Horm in 1966. Compared to β-ecdysone, Ponesterone proves to be 3-100 times more potent in specific neurosensory systems. | | 使用 | Ponasterone A has been used to induce the expression of human huntingtin (HTT). | | 定義 | ChEBI: Ponasterone A is a 2beta-hydroxy steroid, a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 20-hydroxy steroid, a 22-hydroxy steroid, a 6-oxo steroid and a phytoecdysteroid. | | Biochem/physiol Actions | Ponasterone A is an analogue of ecdysone. It induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E. | | 貯蔵 | +4°C |
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