| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Spiroxatrine;8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)Methyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
CAS:1054-88-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | SPIROXATRINE Basic information |
| Product Name: | SPIROXATRINE | | Synonyms: | SPIROXATRINE;R 5188;(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE;8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE;SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5;R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one;Spiroxatrine (R 5188);8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | | CAS: | 1054-88-2 | | MF: | C22H25N3O3 | | MW: | 379.45 | | EINECS: | | | Product Categories: | Serotonin receptor | | Mol File: | 1054-88-2.mol |  |
| | SPIROXATRINE Chemical Properties |
| Melting point | 215.8-218.0 °C | | Boiling point | 602.8±55.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | 0.1 M HCl: moderately soluble | | pka | 15.03±0.20(Predicted) | | form | powder | | color | white |
| | SPIROXATRINE Usage And Synthesis |
| Uses | Spiroxatrine (R 5188) is a SR-1A antagonist. | | Definition | ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines. | | Biological Activity | 5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist. |
| | SPIROXATRINE Preparation Products And Raw materials |
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