肥大脱粒肽
| 中文名称 | 肥大脱粒肽 |
|---|---|
| 中文同义词 | 肥大脱粒肽;黄峰毒素;黄蜂毒素;蜂毒肽GASTRIC MUCIN |
| 英文名称 | MASTOPARAN |
| 英文同义词 | ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2;ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2 4ACOH 6H2O;Mastcelldegranulatingpeptide(Vespulalewisii);Mastoparan from Vespula lewisii;MASTOPARAN TRIFLUOROACETATE SALT >99% PE PTIDE FROM WASP VEN;L-Ile-L-Asn-L-Leu-L-Lys-L-Ala-L-Leu-L-Ala-L-Ala-L-Leu-L-Ala-L-Lys-L-Lys-L-Ile-L-Leu-NH2;MASTOPARAN;MASTOPARAN 4ACOH 6H2O |
| CAS号 | 72093-21-1 |
| 分子式 | C70H131N19O15 |
| 分子量 | 1478.91 |
| EINECS号 | |
| 相关类别 | 多肽;标准品;目录多肽;Peptide;Phospholipase ActivatorsCell Signaling and Neuroscience;Phospholipid Metabolism;Lipids in Cell Signaling;Toxins and Venoms;Wasp;G-Protein |
| Mol文件 | 72093-21-1.mol |
| 结构式 |  |
肥大脱粒肽 性质
| 沸点 | 1676.8±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.150±0.06 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 溶解度 | H2O：1 mg/mL，澄清，无色 |
| 形态 | 白色固体 |
| 酸度系数(pKa) | 13.43±0.46(Predicted) |
| 颜色 | 白色 |
| BRN | 5491949 |
| 序列 | H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2 |
Mastoparan has an amphiphilic nature and is reported to exert a variety of pharmacological and biochemical effects. Mastoparan induces exocytosis of hormones from anterior pituitary cells. Mastoparan stimulation of prolactin secretion is dose-dependent, time-dependent, reversible and required the presence of calcium. Mastoparan causes translocation of protein kinase C activity from a soluble to a membrane-attached form. Mastoparan is able to increase the intracellular Ca 2+ concentration in Fura-2-loaded individual lactotrophs. Mastoparan is also able to interact with GTP-bindmg proteins. Thus, Mastoparan has been shown to facilitate exchange of nucleotides and to stimulate GTPase activity on G-proteins. It has therefore been proposed that the cellular effects of Mastoparan are due to an ability to mimic G-protein-linked agonist-liganded receptors.
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
| 提供商 | 语言 |
|---|---|
|
英文
|
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-P0246 | 肥大脱粒肽 Mastoparan | 72093-21-1 | 1mg | 990元 |
| 2024/01/25 | HY-P0246 | 肥大脱粒肽 Mastoparan | 72093-21-1 | 5mg | 3950元 |