| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:S3QEL-2
CAS:890888-12-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | S3QEL 2 Basic information |
| Product Name: | S3QEL 2 | | Synonyms: | S3QEL 2;1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3,4-dimethylphenyl)-N,N-dipropyl- | | CAS: | 890888-12-7 | | MF: | C19H25N5 | | MW: | 323.44 | | EINECS: | | | Product Categories: | | | Mol File: | 890888-12-7.mol |  |
| | S3QEL 2 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 10 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: slightly soluble | | form | A crystalline solid |
| | S3QEL 2 Usage And Synthesis |
| Description | S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 μM) without altering normal bioenergetics function. It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control level. S3QEL-2 also protects against ROS-induced cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia. | | Uses | S3QEL 2 supresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation. |
| | S3QEL 2 Preparation Products And Raw materials |
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