神经肽-Y (人, 鼠)
| 中文名称 | 神经肽-Y (人, 鼠) |
|---|---|
| 中文同义词 | 神经肽-Y (人, 鼠);NEUROPEPTIDE Y, HUMAN, RAT;NEUROPEPTIDE Y (29-64), AMIDE, HUMAN;神经肽 NEUROPEPTIDE Y(29-64)-NH2, HUMAN;神经肽Y(NPY)(人类,大鼠) |
| 英文名称 | NEUROPEPTIDE Y (HUMAN, RAT) |
| 英文同义词 | NPY FREE ACID (HUMAN, RAT);NPY (HUMAN, RAT);NEUROPEPTIDE Y FREE ACID (HUMAN, RAT);NEUROPEPTIDE Y, HUMAN;NEUROPEPTIDE Y (HUMAN, RAT);TYP-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR;YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY;M.W. 4271.68 C189H285N55O57S |
| CAS号 | 90880-35-6 |
| 分子式 | C189H284N55O57RS |
| 分子量 | 4270.67656 |
| EINECS号 | |
| 相关类别 | 标准品;proteins;Neuropeptide Y (NPY ) receptor;Peptide Receptors |
| Mol文件 | 90880-35-6.mol |
| 结构式 |  |
神经肽-Y (人, 鼠) 性质
| RTECS号 | QQ4064000 |
|---|---|
| 储存条件 | −20°C |
| 溶解度 | H2O：1 mg/mL |
| 形态 | 粉末 |
| 颜色 | 白色 |
| 水溶解性 | Soluble in water (1.5 mg/ml) |
Neuropeptide Y (human) 和阿尔兹海默症相关，能够保护老鼠皮质神经元对抗淀粉样蛋白毒性。
It is showed that Neuropeptide Y (human) is able to protect cortical neurons from Aβ 25-35 toxicity. 2 μM NPY abolishes the toxic effects of Aβ 25-35 at 24 and 48 h. The same effect on neuronal survival is observed in neurons exposed to 1 μM and 0.5 μM Neuropeptide Y (human) pretreatments. Pretreatment with Neuropeptide Y (29-64), amide, human (TFA) Increases NGF Synthesis, reduces NGF mRNA, and restores NGF release in cortical neurons exposed to Aβ 35-25 .
安全信息
| WGK Germany | 3 |
|---|---|
| F | 10-21 |
| 海关编码 | 2937190000 |