| Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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0717-6449896 13886658719 |
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root@zhongyitai.com |
| Products Intro: |
Product Name:13(14)-Epoxy-Docosapentaenoic acid
CAS:895127-64-7
Purity:98+% Package:100ug
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| Company Name: |
Alfa Chemistry
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| Tel: |
1-516-6625404 |
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support@alfa-chemistry.com |
| Products Intro: |
Product Name:(4(Z),7(Z),10Z)-12-[3-(2(Z),5Z)-2,5-octadien-1-yl-2-oxiranyl]-4,7,10-dodecatrienoic acid
CAS:895127-64-7
Purity:95%+ Package:1g;10g;100g;1KG;5KG
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:(±)13(14)-EpDPA
CAS:895127-64-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:(±)13(14)-EpDPA
CAS:895127-64-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | (±)13(14)-EpDPA Basic information |
| Product Name: | (±)13(14)-EpDPA | | Synonyms: | (±)13(14)-EpDPA;13(14)-Epoxy-Docosapentaenoic acid;(4(Z),7(Z),10Z)-12-[3-(2(Z),5Z)-2,5-octadien-1-yl-2-oxiranyl]-4,7,10-dodecatrienoic acid;4,7,10-Dodecatrienoic acid, 12-[3-(2Z,5Z)-2,5-octadien-1-yl-2-oxiranyl]-, (4Z,7Z,10Z)- | | CAS: | 895127-64-7 | | MF: | C22H32O3 | | MW: | 344.49 | | EINECS: | | | Product Categories: | | | Mol File: | 895127-64-7.mol |  |
| | (±)13(14)-EpDPA Chemical Properties |
| Boiling point | 462.8±33.0 °C(Predicted) | | density | 0.994±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 25 mg/mL; DMSO: 20 mg/mL; Ethanol: 50 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL | | pka | 4.58±0.10(Predicted) |
| | (±)13(14)-EpDPA Usage And Synthesis |
| Description | Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid (DHA; ) epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models.1 (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.2 | | References | 1. Morisseau, C., Inceoglu, B., Schmelzer, K., et al. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids J. Lipid Res. 51,3481-3490(2010).
2. Zhang, G., Panigrahy, D., Mahakian, L.M., et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis Proc. Natl. Acad. Sci. USA 110(16),6530-6535(2013). |
| | (±)13(14)-EpDPA Preparation Products And Raw materials |
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