叠氮-六聚乙二醇-丙烯酸琥珀酰亚胺
中文名称 | 叠氮-六聚乙二醇-丙烯酸琥珀酰亚胺 |
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中文同义词 | 叠氮-六聚乙二醇-NHS 酯;叠氮-六聚乙二醇-丙烯酸琥珀酰亚胺;叠氮-六聚乙二醇-琥珀酰亚胺酯;AZIDO-PEG6-NHS ESTER,叠氮-六聚乙二醇-琥珀酰亚胺酯;叠氮-聚乙二醇-羟基琥珀酰亚胺酯 |
英文名称 | Azido-PEG6-NHS ester |
英文同义词 | Azido-PEG6-NHS ester;N3-PEG6-CH2CH2COONHS;CAS_2055014-64-5;Azido-PEG6-NHS ester,N3-PEG6-NHS;N3-PEG6-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-azido-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate;Azido-PEG6-NHS eater |
CAS号 | 2055014-64-5 |
分子式 | C19H32N4O10 |
分子量 | 476.48 |
EINECS号 | |
相关类别 | 基准试剂 |
Mol文件 | 2055014-64-5.mol |
结构式 |
叠氮-六聚乙二醇-丙烯酸琥珀酰亚胺 性质
溶解度 | 溶于水、DMSO、DCM、DMF |
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PEGs
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Alkyl/ether
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Cleavable
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ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.