杜鹃素
| 中文名称 | 杜鹃素 |
|---|---|
| 中文同义词 | 5,7-二羟基-2-(4-羟基苯基)-6,8-二甲基-2,3-二氢苯并吡喃-4-酮;杜鹃素(标准品);杜鹃素;杜鹃素(法尔杜鹃素,5,7-二羟基-2-(4-羟基苯基)-6,8-二甲基-2,3-二氢苯并吡喃-4-酮);FARREROL 杜鹃素;4-羟基苯基-6,8-二甲基-2,3-二氢苯并吡喃-4-酮;法尔杜鹃素,5,7-二羟基-2-;杜鹃素, 来源于杜鹃 |
| 英文名称 | 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE |
| 英文同义词 | 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-diMethylchroMan-4-one;FARREROL;CYRTOPTERINETIN;CYRTPOTERINETIN;5,7,4'-TRIHYDROXY-6,8-DIMETHYLFLAVANONE;6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE;6,8-DIMETHYL-5,7,4'-TRIHYDROXYFLAVANONE;5,7-Dihydroxy-2-(4-hydroxyphenyl) |
| CAS号 | 24211-30-1 |
| 分子式 | C17H16O5 |
| 分子量 | 300.31 |
| EINECS号 | 246-080-2 |
| 相关类别 | 中草药成分;中药对照品;植提标准品;标准品;植物提取物;Flavanones;对照品;精细化工;分析试剂标准品;标准品-对照品;黄酮;标准品 -中药标准品;分析试剂-标准品;标准品，对照品;化工原料 |
| Mol文件 | 24211-30-1.mol |
| 结构式 |  |
杜鹃素 性质
| 熔点 | 212-220 °C |
|---|---|
| 沸点 | 583.0±50.0 °C(Predicted) |
| 密度 | 1.39 |
| 闪点 | 220℃ |
| 储存条件 | 2-8°C |
| 溶解度 | DMSO（微溶）、乙醇（微溶） |
| 形态 | 固体 |
| 酸度系数(pKa) | 8.22±0.40(Predicted) |
| 颜色 | 淡黄色低 |
| LogP | 4.110 (est) |
| CAS 数据库 | 24211-30-1(CAS DataBase Reference) |
Farrerol observably reduces the production of inflammatory mediators including IL-1β, IL-6, TNF-α, COX-2, and iNOS in LPS-induced RAW264.7 cells via suppressing AKT, ERK1/2, JNK1/2, and NF-κB p65 phosphorylation.
Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line.
Farrerol inhibits angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway.
Farrerol overcomes the invasiveness of lung squamous cell carcinoma cells by regulating the expression of inducers of epithelial mesenchymal transition.
Farrerol ameliorates acetaminophen-induced hepatotoxicity via activation of Nrf2 and autophagy.
Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways.
安全信息
| 海关编码 | 29329990 |
|---|
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N0344 | 杜鹃素 Farrerol | 24211-30-1 | 5mg | 1100元 |
| 2024/01/25 | HY-N0344 | 杜鹃素 Farrerol | 24211-30-1 | 10mg | 1850元 |