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ChemicalBook Optimization Suppliers |
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| 化学名: | L-セレノシスチン一水和物 | | 英語化学名: | L-SELENOCYSTINE | | 别名: | l-3,3’-diselenodialanine;3,3'-DISELENO-L-ALANINE;L-SELENOCYSTINE 98%;(R,R)-3,3μ-Diseleno-bis(2-aminopropionic acid), L-Selenocystine;L-Selenocystine,98%;Seleno-L-cystine,(R,R)-3,3′-Diseleno-bis(2-aminopropionic acid), L-Selenocystine;L-Selenocystine Monohydrate;Alanine, 3,3'-diselenodi-, L- | | CAS番号: | 29621-88-3 | | 分子式: | C6H12N2O4Se2 | | 分子量: | 334.09 | | EINECS: | 608-382-6 | | カテゴリ情報: | amino acids | | Mol File: | 29621-88-3.mol |  |
| 融点 | 224.5-229.5 °C (lit.) | | 沸点 | 538.3±60.0 °C(Predicted) | | 貯蔵温度 | 2-8°C | | 溶解性 | Aqueous Acid (Slightly), Aqueous Base (Slightly) | | 外見 | Powder | | 酸解離定数(Pka) | 1.69±0.10(Predicted) | | 色 | Yellow | | 光学活性 (optical activity) | [α]20/D 28°, c = 1 in NaOH | | BRN | 1969559 | | 安定性： | Hygroscopic |
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ACROS
| English |
| | L-セレノシスチン一水和物 Usage And Synthesis |
| 外観 | うすい黄色～褐色粉末～結晶 | | 説明 | L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types. | | 化学的特性 | yellow fine powder | | 使用 | Seleno-L-cystine can be used for the synthesis of:
- Biologically active selenol compounds.
- Non-natural selenylated diamino acids.
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