| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:SGK1 Inhibitor
CAS:1426214-51-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:SGK1 Inhibitor
CAS:1426214-51-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Beijing Biocreative Technology Co., Ltd.
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| Tel: |
15522676233 |
| Email: |
3007606172@qq.com |
| Products Intro: |
Product Name:SGK1 inhibitor
CAS:1426214-51-8
Purity:99% HPLC Package:1.0mg; 5.0mg; 10.0mg; 25.0mg
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:SGK1 Inhibitor
CAS:1426214-51-8
Purity:95% Package:1mg;5mg;10mg
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:SGK1 Inhibitor
CAS:1426214-51-8
|
|
| | SGK1 Inhibitor Basic information |
| Product Name: | SGK1 Inhibitor | | Synonyms: | Benzenesulfonamide, N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-;N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-benzenesulfonamide | | CAS: | 1426214-51-8 | | MF: | C17H12Cl2N6O2S | | MW: | 435.29 | | EINECS: | | | Product Categories: | | | Mol File: | 1426214-51-8.mol |  |
| | SGK1 Inhibitor Chemical Properties |
| Boiling point | 730.5±70.0 °C(Predicted) | | density | 1.660±0.06 g/cm3(Predicted) | | solubility | DMSO: soluble | | form | A solid | | pka | 5.86±0.10(Predicted) |
| | SGK1 Inhibitor Usage And Synthesis |
| Description | SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3β in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kα inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719. |
| | SGK1 Inhibitor Preparation Products And Raw materials |
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