| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. Gold
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:MMP-8 Inhibitor I
CAS:236403-25-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | MMP-8 INHIBITOR I Basic information |
| Product Name: | MMP-8 INHIBITOR I | | Synonyms: | (3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE];MMP-8 INHIBITOR I;MMP 8-I;3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-;MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I) | | CAS: | 236403-25-1 | | MF: | C17H18N2O5S | | MW: | 362.4 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | MMP-8 INHIBITOR I Chemical Properties |
| storage temp. | -20°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | Off-White to Light Yellow |
| | MMP-8 INHIBITOR I Usage And Synthesis |
| Description | MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer. | | Uses | MMP 8-I is a matrix metalloproteinase 8 inhibitor. Matrix metalloproteinases are involved with tight junction protein degradation in endothelial cells. |
| | MMP-8 INHIBITOR I Preparation Products And Raw materials |
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