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Glycolonitrile Basic information
Product Name:Glycolonitrile
Synonyms:FORMALDEHYDE CYANOHYDRIN;2-Hydroxyethanenitrile;alpha-hydroxyacetonitrile;alpha-hydroxymethylcyanide;Cyanomethanol,glycolonitrile;Glycolic nitrile;glycolicacidnitrilesolution;glycolicnitrile
Product Categories:
Mol File:107-16-4.mol
Glycolonitrile Structure
Glycolonitrile Chemical Properties
Melting point -72°C
Boiling point 183°C
density 1.076 g/mL at 20 °C
refractive index n20/D 1.389
Fp 133 °F
Water Solubility >=10 g/100 mL at 20 ºC
Stability:Stable, but may react violently with alkalies. Incompatible with strong oxidizing agents.
CAS DataBase Reference107-16-4(CAS DataBase Reference)
NIST Chemistry ReferenceAcetonitrile, hydroxy-(107-16-4)
EPA Substance Registry SystemFormaldehyde cyanohydrin (107-16-4)
Safety Information
Hazard Codes T+
Risk Statements 26/27/28
Safety Statements 36/37/39-45-36/37-28
RIDADR UN 3276 6.1/PG 1
WGK Germany -
RTECS AM0350000
HazardClass 6.1(a)
PackingGroup I
Hazardous Substances Data107-16-4(Hazardous Substances Data)
MSDS Information
2-Hydroxymethylnitrile English
SigmaAldrich English
Glycolonitrile Usage And Synthesis
Chemical Propertieslight yellow liquid (typically available as a concentrated
Chemical PropertiesFormaldehyde cyanohydrin is a colorless, odorless, oily liquid. Sweet taste (very highly toxic; do not test).
UsesSolvent and organic intermediate.
Production MethodsGlycolonitrile is the result of reaction between formaldehyde and aqueous sodium cyanide in the presence of mineral acid.
General DescriptionOdorless colorless oil with a sweetish taste. Used in the manufacture of intermediates in pharmaceutical production, as a component of synthetic resins, as a chemical intermediate for organic compounds, and as a solvent.
Air & Water ReactionsWater soluble.
Reactivity ProfileGlycolonitrile may undergo spontaneous and violent decomposition. Traces of alkali (base) promote violent polymerization [Lewis].
HazardToxic by ingestion, inhalation, and skin absorption.
Health HazardExtremely toxic, exposure by any route should be avoided; may have fatal consequences; death from asphyxiation may occur similar to that resulting from hydrogen cyanide.
Fire HazardModerate explosion hazard when exposed to heat or by spontaneous chemical reaction in the presence of alkalies if uninhibited. When heated to decomposition, Glycolonitrile emits highly toxic fumes of cyanide and nitrogen oxides. Unstable, may explode on standing. Hazardous polymerization may occur. avoid the presence of alkalis, and exposure to heat.
Potential ExposureFormaldehyde cyanohydrin is used in the manufacture of intermediates in pharmaceutical produc tion and as a component of synthetic resins as a chemical intermediate for organic compounds, and as a solvent.
ShippingUN3276 Nitriles, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required, Potential Inhalation Hazard (Special Provision 5). UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, and exposure to heat. Unless stabilized with a weak acid solution, traces of alka lis may cause violent polymerization.
Tag:Glycolonitrile(107-16-4) Related Product Information
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