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2-NITROBENZYL CHLORIDE

2-NITROBENZYL CHLORIDE Basic information
Product Name:2-NITROBENZYL CHLORIDE
Synonyms:1-Nitro-2-(chloromethyl)benzene;2-(Chloromethyl)nitrobenzene, alpha-Chloro-2-nitrotoluene;2-Nitrobenzyl chloride 99%;2-NITROBENZYL CHLORIDE;A-CHLORO-O-NITROTOLUENE;2-NitrobenzylChloride98%;à-chloro-2-nitrotoluene;α-chloro-2-nitrotoluene
CAS:612-23-7
MF:C7H6ClNO2
MW:171.58
EINECS:210-300-5
Product Categories:
Mol File:612-23-7.mol
2-NITROBENZYL CHLORIDE Structure
2-NITROBENZYL CHLORIDE Chemical Properties
Melting point 46-48 °C (lit.)
Boiling point 127-133 °C/10 mmHg (lit.)
density 1,556 g/cm3
refractive index 1.5557 (estimate)
Fp >230 °F
storage temp. Store below +30°C.
solubility ethanol: soluble98%
form Crystals, Crystalline Powder or Chunks
color Yellow to tan
Water Solubility Soluble in acetone, alcohol benzene, diethyl ether, and ethanol (98%). Insoluble in water.
BRN 388396
Stability:Stable. Incompatible with bases, moisture, acohols, oxidizing agents, amines. Corrodes steel.
CAS DataBase Reference612-23-7(CAS DataBase Reference)
EPA Substance Registry Systemo-Nitrobenzyl chloride (612-23-7)
Safety Information
Hazard Codes C
Risk Statements 34-36
Safety Statements 26-36/37/39-45-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
RTECS XS9092000
F 19-21
HazardClass 8
PackingGroup II
HS Code 29049090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
2-NITROBENZYL CHLORIDE Usage And Synthesis
Chemical Propertiesliquid
Uses2-Nitrobenzyl chloride was used in the synthesis of S-(2-nitrobenzyl)cysteine which was inserted into human erythropoietin. 2-Nitrobenzyl chloride was used to prepare 4,4′-dinitrostillbene.
Uses2-Nitrobenzyl chloride has been used to introduce the photo labile 2-nitrobenzyl protecting group for the phenolic OH group of tyrosine. It is used as a pharmaceutical intermediate.
General DescriptionPale yellow crystals. Insoluble in water. Is thermally unstable.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileA halogenated aromatic nitro compound. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.
Health HazardACUTE/CHRONIC HAZARDS: Toxic. Lachrymator. Causes irritation on contact. Hazardous decomposition products. Mutagen.
Fire Hazard2-NITROBENZYL CHLORIDE is combustible.
Biochem/physiol Actions2-Nitrobenzyl chloride reacts with N-methyldiethanolamine and further reaction of the resulting quaternary diol with thionyl chloride at room temperature yields nitrobenzyl mustard quaternary salts.
2-NITROBENZYL CHLORIDE Preparation Products And Raw materials
Preparation Products2,4-DINITROBENZYL CHLORIDE-->2,2'-DINITRODIBENZYL
Tag:2-NITROBENZYL CHLORIDE(612-23-7) Related Product Information
5-METHYL-2-NITROBENZYL CHLORIDE 2-NITROBENZYL CHLORIDE 2-Nitrobenzoyl chloride 2,4-DINITROBENZYL CHLORIDE m-Nitrobenzoyl chloride 4-METHYL-3-NITROBENZYL CHLORIDE 97%,4-METHYL-3-NITROBENZYL CHLORIDE 2-ACETOXY-5-NITROBENZYL CHLORIDE 4-NITROBENZYL CHLORIDE 99%,P-NITROBENZYL CHLORIDE,Benzene, 1-(chloromethyl)-4-nitro-: (p-Nitrobenzyl chloride),4-NITROBENZYL CHLORIDE 2-METHYL-3-NITROBENZYL CHLORIDE 2-Methyl-5-Nitrobenzyl Chloride 3,5-DINITROBENZYL CHLORIDE 3-NITROBENZYL CHLORIDE, 98.5%,M-NITROBENZYL CHLORIDE,3-Nitrobenzyl chloride 96%,3-NITROBENZYL CHLORIDE 2-Nitrotoluene 2-NITRO-3,4,5-TRIFLUOROBENZOYL CHLORIDE 4-CHLORO-2-NITROBENZYL CHLORIDE ALPHA-CHLORO-2-NITROBENZALDOXIME 2-NITRO-4-TRIFLUOROMETHYL-BENZOYL CHLORIDE 2-METHYL-6-NITROBENZOYL CHLORIDE