Ac-delta-endorphin (human)

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Ac-delta-endorphin (human) Basic information
Product Name:Ac-delta-endorphin (human)
Synonyms:B-endorphin fragment 1-27;B-ENDORPHIN FRAGMENT 1-27, HUMAN;BETA-ENDORPHIN, FRAGMENT 1-27;fragment1-27;β-endorphin human fragment 1-27;beta-endorphin, human, fragment 1-27;ACETYL, BETA-ENDORPHIN (1-27), HUMAN;ACETYL-TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-PHE-LYS-ASN-ALA-ILE-ILE-LYS-ASN-ALA-TYR-OH
CAS:76622-84-9
MF:C139H217N33O40S
MW:3022.47
EINECS:
Product Categories:Endorphins;Opioid Peptides;Peptides for Cell Biology
Mol File:76622-84-9.mol
Ac-delta-endorphin (human) Structure
Ac-delta-endorphin (human) Chemical Properties
storage temp. −20°C
SequenceTyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Ac-delta-endorphin (human) Usage And Synthesis
Usesβ-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia[1][2].
References[1] Mansour A, et al. The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Res. 1995 Nov 27;700(1-2):89-98. DOI:10.1016/0006-8993(95)00928-j
[2] Nicolas P, et al. Beta-endorphin-(1-27) is a naturally occurring antagonist to etorphine-induced analgesia. Proc Natl Acad Sci U S A. 1985 May;82(10):3178-81. DOI:10.1073/pnas.82.10.3178
Ac-delta-endorphin (human) Preparation Products And Raw materials
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alpha-Cgrp (19-37) (human) ENTEROSTATIN, HUMAN GASTRIC INHIBITORY POLYPEPTIDE (6-30) AMIDE (HUMAN) beta-endorphin (6-31) Big Gastrin I Human CCK-33 (HUMAN) ACETYL-BETA-ENDORPHIN (HUMAN) H-Ser-Ala-Glu-Glu-Tyr-Glu-Tyr-Pro-Ser-OH Methionine enkephalinamide acetate salt Ac-delta-endorphin (human) H-Ala-Ala-Ala-Tyr-OH H-Pro-Leu-Gly-NH2 H2O Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu Des-Tyr1-methionine enkephalinamide acetate salt Met-enkephalinamide