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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
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Product Name:N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
CAS:479050-94-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
CAS:479050-94-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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021-69568360 18916172912 |
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order@med-bio.cn |
| Products Intro: |
Product Name:C16-HSL
CAS:479050-94-7
Purity:98% Package:5mg; 10mg; 50mg; 25mg Remarks:Medbio
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| Company Name: |
Shanghai Universal Biotech Co.,Ltd
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18768175414 |
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gaojun@univ-bio.com |
| Products Intro: |
Product Name:N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
CAS:479050-94-7
Package:10mg Remarks: 见优宁维官网
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:N-cis-Hexadec-9Z-enoyl-L-homoserine lactone
CAS:479050-94-7
Purity:98% Package:5mg;10mg;25mg
|
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| | C16-HSL Basic information |
| Product Name: | C16-HSL | | Synonyms: | C16:1-DELTA9-(L)-HSL;C16-HSL;N-CIS-HEXADEC-9-ENOYL-L-HOMOSERINE LACTONE;PALMITOLEYL HOMOSERINE LACTONE;N-cis-hexadec-9Z-enoyl-L-Homoserine lactone;9-Hexadecenamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-, (9Z)-;(Z)-N-[(3S)-2-oxooxolan-3-yl]hexadec-9-enamide | | CAS: | 479050-94-7 | | MF: | C20H35NO3 | | MW: | 337.5 | | EINECS: | | | Product Categories: | | | Mol File: | 479050-94-7.mol |  |
| | C16-HSL Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) 1:1: 0.5 mg/ml | | form | A crystalline solid |
| | C16-HSL Usage And Synthesis |
| Description | Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.1 This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.2 Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.3 N-cis-hexadec-9Z-enoyl-L-Homoserine lactone is a long-chain AHL that functions as a quorum sensing signaling molecule in strains of S. meliloti.4,5,6,7 Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therapy in the treatment of infectious diseases.8 | | References | 1. González, J.E., and Keshavan, N.D. Messing with bacterial quorum sensing Microbiol. Mol. Biol. Rev. 70(4),859-875(2006).
2. Gould, T.A., Herman, J., Krank, J., et al. Specificity of acyl-homoserine lactone syntheses examined by mass spectrometry J. Bacteriol. 188(2),773-783(2006).
3. Penalver, C.G.N., Morin, D., Cantet, F., et al. Methylobacterium extorquens AM1 produces a novel type of acyl-homoserine lactone with a double unsaturated side chain under methylotrophic growth conditions FEBS Lett. 580(2),561-567(2006).
4. Teplitski, M., Eberhard, A., Gronquist, M.R., et al. Chemical identification of N-acyl homoserine lactone quorum-sensing signals produced by Sinorhizobium meliloti strains in defined medium Arch. Microbiol. 180(6),494-497(2003).
5. Gao, M., Chen, H., Eberhard, A., et al. sinI- and expR-dependent quorum sensing in Sinorhizobium meliloti J. Bacteriol. 187(23),7931-7944(2005).
6. Marketon, M.M., Glenn, S.A., Eberhard, A., et al. Quorum sensing controls exopolysaccharide production in Sinorhizobium meliloti J. Bacteriol. 185(1),325-331(2003).
7. Marketon, M., Gronquist, M.R., Eberhard, A., et al. Characterization of the Sinorhizobium meliloti sinR/sinI locus and the production of novel N-Acyl homoserine lactones J. Bacteriol. 184(20),5686-5695(2002).
8. Cegelski, L., Marshall, G.R., Eldridge, G.R., et al. The biology and future prospects of antivirulence therapies Nat. Rev. Microbiol. 6(1),17-27(2008). |
| | C16-HSL Preparation Products And Raw materials |
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