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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt)
CAS:157542-47-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
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Product Name:D-myo-Inositol-1,4,5,6-tetraphosphate sodium salt
CAS:157542-47-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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021-69568360 18916172912 |
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order@med-bio.cn |
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Product Name:D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt)
CAS:157542-47-7
Purity:98% Package:100ug; 500ug; 1mg Remarks:Medbio
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Shanghai Haohong Scientific Co., Ltd.
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Product Name:D-myo-Inositol, 1,4,5,6-tetrakis(dihydrogen phosphate), tetrasodium salt
CAS:157542-47-7
Purity:98%
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| | D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) Basic information |
| | D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) Chemical Properties |
| storage temp. | Store at -20°C | | form | A lyophilized powder | | Water Solubility | 50mg/mL in water |
| | D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) Usage And Synthesis |
| Description | D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.1 Ins(1,4,5,6)-P4 antagonizes epidermal growth factor (EGF) signalling through the phosphatidylinositol 3-kinase pathway.1 Ins(1,4,5,6)-P4 (tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.2 | | References | 1. Eckmann, L., Rudolf, M.T., Ptasznik, A., et al. D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways Proc. Natl. Acad. Sci. USA 94,14456-14460(1997).
2. DeLisle, S., Radenberg, T., Wintermantel, M.R., et al. Second messenger specificity of the inositol trisphosphate receptor: Reappraisal based on novel inositol phosphates Am. J. Physiol. 266(2 Pt 1),C429-C436(1994). |
| | D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) Preparation Products And Raw materials |
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